The liver plays a critical role in sepsis, which is a serious worldwide public health problem. A
novel mechanism of controlled cell death called ferroptosis has recently been described …

Background Wenqingyin (WQY) is a classic traditional Chinese medicine formula used to
treat various inflammatory diseases. However, its protective activity against ferroptosis in the …

Liver fibrosis is a progression of chronic liver disease, which lacks effective therapies in the
world. Attractively, more and more evidences show that natural products are safe and …

Ferroptosis has been implicated in the pathophysiological progression of a variety of
diseases. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a key regulator of cellular …

Ferroptosis is a reactive oxygen species (ROS)-and iron-dependent form of regulated cell
death (RCD), playing critical roles in organ injury and targeting therapy of cancers. Previous …

Dimethyl fumarate (DMF), a therapeutic agent for relapsing-remitting multiple sclerosis, has
cytoprotective and antioxidant effects. Ferroptosis, a pathological cell death process, is …

Background Ferroptosis is a brand-new type of controlled cell death that is distinguished by
its reliance on iron and the production of lipid peroxidation. The role of ferroptosis in …

Ferroptosis is recently reported as a new mode of regulated cell death. It is triggered by
disturbed redox homeostasis, overloaded iron and increased lipid peroxidation. Howerver …

Itaconate, a metabolite produced during inflammatory macrophage activation, has been
extensively described to be involved in immunoregulation, oxidative stress, and lipid …

Background Currently, the existing treatments have not cured the liver fibrosis thoroughly.
Ferroptosis is a newly discovered way of cell death, which is closely related to many …