Drives Blunted by Time: The Effects of Aging on Motivational Behaviors and Responses to Social Isolation in Mice
HC Lei - 2023 - search.proquest.com
Mental health in the elderly is an escalating social problem as the world population ages
rapidly. Older adults are more susceptible to stressors like social isolation, which is a …
rapidly. Older adults are more susceptible to stressors like social isolation, which is a …
[HTML][HTML] Emotional behavior in middle-aged rats: implications for geriatric psychopathologies
M Moretti, AG de Souza, G de Chaves… - Physiology & …, 2011 - Elsevier
Clinical findings reveal that middle-aged patients are more susceptible to suffer from
psychiatric disorders than older ones. However, little is known about the emotional behavior …
psychiatric disorders than older ones. However, little is known about the emotional behavior …
Aging and the social-emotional brain
E Soria-Gómez, J Piriz, I Torres-Alemán - Frontiers in Aging …, 2024 - frontiersin.org
In modern society, life expectancy increases year after year due in part to medical and
scientific advances. However, at the same time, other pathological conditions appear in …
scientific advances. However, at the same time, other pathological conditions appear in …
Aged rats are hypo-responsive to acute restraint: implications for psychosocial stress in aging
HM Buechel, J Popovic, K Staggs… - Frontiers in aging …, 2014 - frontiersin.org
Cognitive processes associated with prefrontal cortex and hippocampus decline with age
and are vulnerable to disruption by stress. The stress/stress hormone/allostatic load …
and are vulnerable to disruption by stress. The stress/stress hormone/allostatic load …
Social isolation stress impairs passive avoidance learning in senescence-accelerated mouse (SAM)
Y Chida, N Sudo, J Mori, C Kubo - Brain research, 2006 - Elsevier
Despite cumulative evidence showing the detrimental effect of psychosocial stress on the
learning/memory functions in dementia diseases, the precise neurobiological mechanisms …
learning/memory functions in dementia diseases, the precise neurobiological mechanisms …
Differential effects of chronic stress in young-adult and old female mice: cognitive-behavioral manifestations and neurobiological correlates
A Lotan, T Lifschytz, G Wolf, S Keller, H Ben-Ari… - Molecular …, 2018 - nature.com
Stress-related psychopathology is highly prevalent among elderly individuals and is
associated with detrimental effects on mood, appetite and cognition. Conversely, under …
associated with detrimental effects on mood, appetite and cognition. Conversely, under …
Reduced activity of glutamatergic neurons in the prelimbic medial prefrontal cortex underlies the inherent aging-related physiological reduction in social dominance
Q Shan, X Lin, X Yu, W Guo… - The Journals of …, 2023 - academic.oup.com
Human society is aging, and the percentage of the population of older adults is increasing at
an unprecedented rate. It is increasingly appreciated that social behaviors change with …
an unprecedented rate. It is increasingly appreciated that social behaviors change with …
Deficits in social behavior precede cognitive decline in middle-aged mice
F Boyer, F Jaouen, EC Ibrahim… - Frontiers in Behavioral …, 2019 - frontiersin.org
An extensive literature details deterioration of multiple brain functions, especially memory
and learning, during aging in humans and in rodents. In contrast, the decline of social …
and learning, during aging in humans and in rodents. In contrast, the decline of social …
Parallel declines in cognition, motivation, and locomotion in aging mice: association with immune gene upregulation in the medial prefrontal cortex
Aging in humans is associated with parallel changes in cognition, motivation, and motoric
performance. Based on the human aging literature, we hypothesized that this constellation …
performance. Based on the human aging literature, we hypothesized that this constellation …
Age-related decrease in stress responsiveness and proactive coping in male mice
HJ Oh, M Song, YK Kim, JR Bae, SY Cha… - Frontiers in aging …, 2018 - frontiersin.org
Coping is a strategic approach to dealing with stressful situations. Those who use proactive
coping strategies tend to accept changes and act before changes are expected. In contrast …
coping strategies tend to accept changes and act before changes are expected. In contrast …