[HTML][HTML] Free radicals properties of gamma-irradiated penicillin-derived antibiotics: piperacillin, ampicillin, and crystalline penicillin

S Wilczyński, B Pilawa, R Koprowski, Z Wróbel… - Radiation and …, 2014 - Springer
The aim of this work was to determine the concentrations and properties of free radicals in
piperacillin, ampicillin, and crystalline penicillin after gamma irradiation. The radicals were …

Feasibility of radiation sterilization and dosimetric features of ampicillin: an electron spin resonance study

Ş Çolak - Radiation Effects and Defects in Solids, 2016 - Taylor & Francis
In the present work, it was aimed to identify radical species produced by gamma irradiation
(3–34 kGy) of solid ampicillin, to determine its spectroscopic, dosimetric, stability and kinetic …

EPR studies of free radicals decay and survival in gamma irradiated aminoglycoside antibiotics: sisomicin, tobramycin and paromomycin

S Wilczyński, B Pilawa, R Koprowski, Z Wróbel… - European Journal of …, 2012 - Elsevier
Radiation sterilization technology is more actively used now that any time because of its
many advantages. Gamma radiation has high penetrating power, relatively low chemical …

The stability studies of penicillin and ampicillin following γ-irradiation in the solid state

R Beteshobabrud, F Nabardi - 2009 - sid.ir
The effect of 10 and 25 kGy g-irradiation on PENICILLIN G plus procaine and sodium
AMPICILLIN has been assessed by different chemical and microbiological analytical …

Influence of ionizing radiation on benzathine penicillin G by means of EPR spectroscopy

IY Dicle - Journal of Radioanalytical and Nuclear Chemistry, 2016 - Springer
Benzathine penicillin G (BPG) in powder form was exposed to a range of different doses of
60 Co gamma radiation to investigate the effects of ionizing radiation using electron …

Effects of radiation on carbapenems: ESR identification and dosimetric features of gamma irradiated solid meropenem trihydrate

S Tepe, M Polat, M Korkmaz - Radiation Effects and Defects in …, 2006 - Taylor & Francis
In the present work, effects of gamma radiation on solid meropenem trihydrate (MPT), which
is the active ingredient of carbapenem antibiotics, were investigated by electron spin …

Radiation-induced effects on cefotaxime: ESR study

JP Basly, I Basly, M Bernard - Free radical research, 1998 - Taylor & Francis
As an alternative to heat and gas exposure sterilization, ionizing radiation is gaining interest
as sterilization process for medicinal products. Detection and dosimetry of pharmaceuticals …

Electron Spin Resonance (ESR) Investigation of Gamma-Irradiated Antibiotic Azithromycin

AA Wassel - Journal of Advanced Scientific Research, 2012 - sciensage.info
The use of ionizing radiation for sterilization of pharmaceutical is now a well established
technology. Electron spin resonance (ESR) spectroscopy was used to investigate the …

[PDF][PDF] UV-Vis and FTIR Spectroscopic Investigations of Gamma-Ray Irradiated Antibiotics

A Smarandache, R Moeller, ML Pascu - Rom. Rep. Phys, 2018 - rrp.nipne.ro
The effect of gamma irradiation on three antibiotics (Nalidixic acid, Spectinomycin, and
Rifampicin) were studied. The drugs were exposed to different doses of radiation emitted by …

The radiation-sterilization of semi-synthetic penicillins

GP Jacobs - The International Journal of Applied Radiation and …, 1979 - Elsevier
Gamma-irradiation in the dry state of the semi-synthetic penicillins, amoxycillin trihydrate,
flucloxacillin-Na, methicillin-Na results in minimal degradation even following a 5 Mrad …