[HTML][HTML] Artesunate: A review of its therapeutic insights in respiratory diseases

J Zhang, Y Li, J Wan, M Zhang, C Li, J Lin - Phytomedicine, 2022 - Elsevier
Background Artesunate, as a semi-synthetic artemisinin derivative of sesquiterpene lactone,
is widely used in clinical antimalarial treatment due to its endoperoxide group. Recent …

Anti-malarial drug, artemisinin and its derivatives for the treatment of respiratory diseases

DHJ Cheong, DWS Tan, FWS Wong, T Tran - Pharmacological research, 2020 - Elsevier
Artemisinins are sesquiterpene lactones with a peroxide moiety that are isolated from the
herb Artemisia annua. It has been used for centuries for the treatment of fever and chills, and …

[HTML][HTML] Artesunate inhibits airway remodeling in asthma via the MAPK signaling pathway

M Zhang, J Lin, J Zhang, R Zhao, J Wan… - Frontiers in …, 2023 - frontiersin.org
Background: Artesunate (ART), is a semi-synthetic water-soluble artemisinin derivative
extracted from the plant Artemisia annua, which is often used to treating malaria. In vivo and …

Untargeted proteomics and systems-based mechanistic investigation of artesunate in human bronchial epithelial cells

KC Ravindra, WE Ho, C Cheng, LC Godoy… - Chemical research in …, 2015 - ACS Publications
The antimalarial drug artesunate is a semisynthetic derivative of artemisinin, the principal
active component of a medicinal plant Artemisia annua. It is hypothesized to attenuate …

[HTML][HTML] Medicinal and mechanistic overview of artemisinin in the treatment of human diseases

AM Posadino, R Giordo, G Pintus… - Biomedicine & …, 2023 - Elsevier
Artemisinin (ART) is a bioactive compound isolated from the plant Artemisia annua and has
been traditionally used to treat conditions such as malaria, cancer, viral infections, bacterial …

[HTML][HTML] Antiviral and immunomodulation effects of Artemisia

SG Kshirsagar, RV Rao - Medicina, 2021 - mdpi.com
Background and Objectives: Artemisia is one of the most widely distributed genera of the
family Astraceae with more than 500 diverse species growing mainly in the temperate zones …

[HTML][HTML] RETRACTED: Artemisia Extracts and Artemisinin-Based Antimalarials for COVID-19 Management: Could These Be Effective Antivirals for COVID-19 …

PK Agrawal, C Agrawal, G Blunden - Molecules, 2022 - mdpi.com
As the world desperately searches for ways to treat the coronavirus disease 2019 (COVID-
19) pandemic, a growing number of people are turning to herbal remedies. The Artemisia …

More insights into the pharmacological effects of artemisinin

A Zyad, M Tilaoui, A Jaafari, MA Oukerrou… - Phytotherapy …, 2018 - Wiley Online Library
Artemisinin is one of the most widely prescribed drugs against malaria and has recently
received increased attention because of its other potential biological effects. The aim of this …

[HTML][HTML] Artemisia annua: trials are needed for COVID‐19

FU Haq, M Roman, K Ahmad, SU Rahman… - Phytotherapy …, 2020 - ncbi.nlm.nih.gov
Beginning in December 2019, an increasing number of cases of novel coronavirus,
designated SARS-CoV-2, has caused worldwide outbreak of respiratory infection now …

[HTML][HTML] Artemisinin based nanomedicine for therapeutic applications: recent advances and challenges

S Pradhan, A Mishra, S Sahoo, S Pradhan… - Pharmacological …, 2022 - Elsevier
Malaria and cancers still existed as a prevalent life-threatening ailment lacking vaccine
owing to numerous pharmacological drawbacks such as high toxicity, low solubility and low …