The development of precision medicine strategies requires prior knowledge of the genetic
background of the target population. However, despite the availability of data from admixed …

Precision medicine is predicted to revolutionize the clinical practice of medicine, in part by
using molecular biomarkers to assess patients' risk, prognosis, and therapeutic response …

EPIGEN-Brazil is one of the largest Latin American initiatives at the interface of human
genomics, public health, and computational biology. Here, we present two resources to …

Whilst the underlying principles of precision medicine are comparable across the globe,
genomic references, health practices, costs and discrimination policies differ in Asian …

In the post-genomic era, genomic medicine interventions as a key component of
personalized medicine and tailored-made health care are greatly anticipated following …

Personalized or precision medicine is meant to distinguish tailored treatment from trial and
error. The contemporary concept has evolved to specifically include the 'omic profile of a …

Despite the tremendous growth of the DNA sequencing data in the last decade, our
understanding of the human genome is still in its infancy. To understand the implications of …

Background Historically, geneticists have relied on genotyping arrays and imputation to
study human genetic variation. However, an underrepresentation of diverse populations has …

Underrepresentation of non-European (EUR) populations hinders growth of global precision
medicine. Resources such as imputation reference panels that match the study population …

Recent evidence shows how patients' unique genetic makeup can affect disease outcomes
and the increasing availability of targeted treatments promises a future in health care …