Experimental models of hepatocellular carcinoma—a preclinical perspective

A Blidisel, I Marcovici, D Coricovac, F Hut… - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is characterized by a broad molecular
and genetic heterogeneity, which makes it a challenging subject in terms of the underlying …

In vivo and in vitro models of hepatocellular carcinoma: current strategies for translational modeling

GR Romualdo, K Leroy, CJS Costa, GB Prata… - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is a highly incident and deadly malignant
neoplasia, and only a few anti-HCC drugs are currently available. Thus, the development of …

Preclinical mouse models of hepatocellular carcinoma: An overview and update

CY Gu, TKW Lee - Experimental cell research, 2022 - Elsevier
Hepatocellular carcinoma (HCC) is by far the most common histological subtype of primary
liver cancer. HCC often originates from chronic liver injuries and inflammation, subsequently …

Mouse models of hepatocellular carcinoma

R Carlessi, J Köhn-Gaone, J Olynyk… - Hepatocellular …, 2019 - espace.curtin.edu.au
Hepatocellular carcinoma (HCC) represents a major and steadily increasing global health
challenge as the most common primary liver malignancy and leading cause of death in …

[HTML][HTML] Experimental models of hepatocellular carcinoma

P Newell, A Villanueva, SL Friedman, K Koike… - Journal of …, 2008 - Elsevier
Hepatocellular carcinoma (HCC) is a common and deadly cancer whose pathogenesis is
incompletely understood. Comparative genomic studies from human HCC samples have …

Experimental models of hepatocellular carcinoma: developments and evolution

L Wu, ZY Tang, Y Li - Journal of cancer research and clinical oncology, 2009 - Springer
Hepatocellular carcinoma (HCC) is one of the most common malignancies in the world. The
biological mechanisms of hepatocarcinogenesis and progression are poorly understood …

Mouse models of liver cancer

JM Caviglia, RF Schwabe - Mouse Models of Cancer: Methods and …, 2015 - Springer
Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide, and the third
leading cause of cancer mortality. The great majority of patients are not eligible for curative …

[HTML][HTML] Mouse models for liver cancer

L Bakiri, EF Wagner - Molecular oncology, 2013 - Elsevier
Hepatocellular carcinoma (HCC), the most common form of primary liver cancer is the third
leading cause of cancer-related cell death in human and the fifth in women worldwide. The …

Mouse models of hepatocellular carcinoma: classification, advancement, and application

S Liu, F Huang, G Ru, Y Wang, B Zhang, X Chen… - Frontiers in …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is the subtype of liver cancer with the highest incidence,
which is a heterogeneous malignancy with increasing incidence rate and high mortality. For …

Hepatocellular carcinoma: insight from animal models

Y Li, ZY Tang, JX Hou - Nature reviews Gastroenterology & hepatology, 2012 - nature.com
Hepatocellular carcinoma (HCC) ranks as the third most common cause of death from
cancer worldwide. Although major risk factors for the development of HCC have been …