Apixaban thromboprophylaxis in ambulatory patients with cancer and obesity: insights from the AVERT trial

N Potere, M Di Nisio, E Porreca, TF Wang… - Thrombosis research, 2023 - Elsevier
Background The use of direct oral anticoagulants (DOACs) in obese patients is uncertain. It
is unclear if body mass index (BMI) affects the safety and efficacy of DOACs for the primary …

Apixaban in low‐weight patients with cancer‐associated thrombosis: A cross sectional study of drug levels

V Bravo Villa, J Romero… - … and Practice in …, 2021 - Wiley Online Library
Introduction Apixaban, a direct factor Xa inhibitor, has been shown to be at least as safe and
probably more effective than dalteparin for the treatment of cancer‐associated thrombosis …

Cost–utility analysis of apixaban compared with usual care for primary thromboprophylaxis in ambulatory patients with cancer

M Kimpton, S Kumar, PS Wells, D Coyle, M Carrier… - CMAJ, 2021 - Can Med Assoc
Background: Apixaban (2.5 mg) taken twice daily has been shown to substantially reduce
the risk of venous thromboembolism (VTE) compared with placebo for the primary …

[HTML][HTML] Cost-utility analysis of apixaban compared to usual care for the primary thromboprophylaxis of ambulatory cancer patients initiating chemotherapy

M Kimpton, S Kumar, PS Wells, M Carrier, K Thavorn - Blood, 2019 - Elsevier
Introduction: Apixaban 2.5 mg twice daily has been shown to significantly reduce the risk of
venous thromboembolism (VTE) compared to placebo for the primary thromboprophylaxis of …

What's new in the prevention and treatment of cancer-associated thrombosis?

M Kimpton, M Carrier - Hematology 2014, the American Society …, 2019 - ashpublications.org
Venous thromboembolism (VTE) is a common complication in ambulatory cancer patients
receiving chemotherapy. Current clinical guidelines recommend against the use of routine …

“Low dose apixaban as secondary prophylaxis of venous thromboembolism in cancer patients—30 months follow‐up”: Comment from Serrao et al.

A Serrao, GM Assanto, F Malfona… - Journal of Thrombosis …, 2022 - jthjournal.org
Dear Editor, We appreciated reading the original article titled “Low dose apixaban as
secondary prophylaxis of venous thromboembolism in cancer patients–30 months follow up” …

A comprehensive review of DOACs for cancer associated VTE prophylaxis or treatment

EJ Brea, BC Tiu, JM Connors - Postgraduate Medicine, 2021 - Taylor & Francis
Cancer is a leading cause of venous thromboembolism (VTE), which contributes to
significant morbidity and mortality in these patients. Increased thrombotic risk in cancer …

D‐dimer enhances risk‐targeted thromboprophylaxis in ambulatory patients with cancer

V Kumar, JR Shaw, NS Key, A Ilich, R Mallick… - The …, 2020 - academic.oup.com
Background Thromboprophylaxis for ambulatory patients with cancer is effective, although
uncertainties remain on who should be targeted. Using D‐dimer values from individuals …

Apixaban for the prevention of venous thromboembolism in high-risk ambulatory cancer patients receiving chemotherapy: rational and design of the AVERT trial

M Kimpton, PS Wells, M Carrier - Thrombosis Research, 2018 - Elsevier
Patients with active cancer have a heightened risk of venous thromboembolism (VTE). This
risk is further increased by the initiation of chemotherapy. Although previous studies have …

Safety and efficacy of apixaban thromboprophylaxis in cancer patients with metastatic disease: a post-hoc analysis of the AVERT trial

W Knoll, R Mallick, PS Wells, M Carrier - Thrombosis Research, 2021 - Elsevier
Background The risk of venous thromboembolism (VTE) is increased in patients with active
cancer and the risk is highest in those with metastatic disease. The risks and benefits of …