Innovative strategies to improve hematopoietic stem cell transplant outcomes in myelofibrosis

J Perram, DM Ross, D McLornan… - American Journal of …, 2022 - Wiley Online Library
Myelofibrosis (MF) is a clonal myeloproliferative neoplasm characterized by inflammation,
marrow fibrosis, and an inherent risk of blastic transformation. Hematopoietic allogeneic …

[HTML][HTML] Impact of high-molecular-risk mutations on transplantation outcomes in patients with myelofibrosis

R Tamari, F Rapaport, N Zhang, C McNamara… - Biology of Blood and …, 2019 - Elsevier
Mutational profiling has demonstrated utility in predicting the likelihood of disease
progression in patients with myelofibrosis (MF). However, there is limited data regarding the …

Hematopoietic stem cell transplantation for myelofibrosis: where are we now?

AG Fleischman, RT Maziarz - Current opinion in hematology, 2013 - journals.lww.com
Myelofibrosis is a rare hematologic malignancy with limited curative therapeutic options.
Significant advances in our understanding of disease pathogenesis have led to new targets …

Allogeneic haematopoietic cell transplantation for myelofibrosis: a real‐life perspective

M Savani, R Dulery, AH Bazarbachi… - British Journal of …, 2021 - Wiley Online Library
Myelofibrosis (MF) is a clonal stem cell neoplasm with heterogeneous clinical phenotypes
and well‐established molecular drivers. Allogeneic haematopoietic stem cell transplantation …

2024 update on allogeneic hematopoietic stem cell transplant for myelofibrosis: A review of current data and applications on risk stratification and management

H Ali, A Bacigalupo - American Journal of Hematology, 2024 - Wiley Online Library
Background Allogeneic hemopoietic stem cell transplantation (HSCT) currently remains the
only curative treatment for patients with myelofibrosis (MF). Transplant related mortality …

Management of myelofibrosis: from diagnosis to new target therapies

A Iurlo, D Cattaneo, C Bucelli - Current Treatment Options in Oncology, 2020 - Springer
Opinion statement Myelofibrosis (MF) is a clonal disorder of the pluripotent hematopoietic
stem cell, whose clinical manifestations can be extremely heterogeneous, including …

Allogeneic hematopoietic stem-cell transplantation for myelofibrosis: a practical review

N Farhadfar, S Cerquozzi, M Patnaik… - Journal of oncology …, 2016 - ascopubs.org
Myelofibrosis is a myeloproliferative neoplasm with cardinal features of extramedullary
hematopoiesis, hepatosplenomegaly, cytopenias, and constitutional symptoms that result in …

Current challenges in stem cell transplantation in myelofibrosis

N Kröger - Current hematologic malignancy reports, 2015 - Springer
Primary or post-ET/PV myelofibrosis is one of the Philadelphia-negative myeloproliferative
neoplasms with worst survival. Allogeneic stem cell transplantation (ASCT) can cure a …

[HTML][HTML] Allogeneic stem cell transplantation in myelofibrosis

T Jain, RA Mesa, JM Palmer - Biology of Blood and Marrow Transplantation, 2017 - Elsevier
Myeloproliferative neoplasm (MPN) is a category in the World Health Organization
classification of myeloid tumors. BCR-ABL1–negative MPN is a subcategory that includes …

[HTML][HTML] Hematopoietic cell transplantation for myelofibrosis: the dynamic international prognostic scoring system plus risk predicts post-transplant outcomes

BTS Bannow, RB Salit, BE Storer, EA Stevens… - Biology of Blood and …, 2018 - Elsevier
Hematopoietic cell transplantation (HCT) provides potentially curative treatment for patients
with myelofibrosis (MF). HCT outcomes are associated with the Dynamic International …