Simple Summary Nitric oxide and arginine metabolism in colorectal cancer (CRC) holds
potential for therapeutic intervention. We hypothesized that it can be modulated by oxicams …

The L-arginine/NO pathway holds promise as a source of potential therapy target and
biomarker; yet, its status and utility in esophageal squamous cell carcinoma (ESCC) is …

Purpose: Considering the contradictory literature data about the role of nitric oxide (NO) in
colon carcinogenesis, the purpose of this study was to examine the changes of L-arginine …

Nitric oxide (NO) is a short-lived pleiotropic regulator and is required for numerous
pathophysiological functions, including macrophage-mediated immunity and cancer. It is a …

Nitric oxide (NO) is a pleiotrophic regulator, pivotal to numerous biological processes,
including vasodilation, neurotransmission, and macrophage-mediated immunity. The highly …

Background & Aims Chronic inflammation in colon section is associated with an increased
risk of colorectal cancer (CRC). Proinflammatory cytokines were produced in a tumor …

Colon cancer is the third most common cancer and the second leading cause of cancer-
related death in the United States, emphasizing the need for the discovery of new cellular …

Colorectal cancer is the leading cause of death from cancer globally. The current treatment
protocol still heavily relies on early detection and surgery. The molecular mechanisms …

Nitric oxide (NO) is involved in various physiological functions and its role in tumorigenesis
has been well studied. A large majority of human and experimental tumors appear to …

Metabolic reprogramming is a hallmark of cancer, which is still far from being fully
understood in colorectal cancer. In order to characterize the metabolic changes in colorectal …