Modern epigenetics methods in biological research
Y Li - Methods, 2021 - Elsevier
The definition of epigenetics refers that molecular modifications on DNA that can regulate
gene activity are independent of DNA sequence and mitotically stable. Notably, epigenetics …
gene activity are independent of DNA sequence and mitotically stable. Notably, epigenetics …
[HTML][HTML] Mapping epigenetic modifications by sequencing technologies
The “epigenetics” concept was first described in 1942. Thus far, chemical modifications on
histones, DNA, and RNA have emerged as three important building blocks of epigenetic …
histones, DNA, and RNA have emerged as three important building blocks of epigenetic …
Introduction to epigenomics and epigenome-wide analysis
MJ Fazzari, JM Greally - Statistical Methods in Molecular Biology, 2010 - Springer
Epigenetics is the study of heritable change other than those encoded in DNA sequence.
Cytosine methylation of DNA at CpG dinucleotides is the most well-studied epigenetic …
Cytosine methylation of DNA at CpG dinucleotides is the most well-studied epigenetic …
[HTML][HTML] DNA methylation analysis: choosing the right method
S Kurdyukov, M Bullock - Biology, 2016 - mdpi.com
In the burgeoning field of epigenetics, there are several methods available to determine the
methylation status of DNA samples. However, choosing the method that is best suited to …
methylation status of DNA samples. However, choosing the method that is best suited to …
Hunting for the 5th base: Techniques for analyzing DNA methylation
O Ammerpohl, JI Martín-Subero, J Richter… - … et Biophysica Acta (BBA …, 2009 - Elsevier
BACKGROUND: In the recent past large progress has been made in the analysis of the
epigenome, the entirety of epigenetic modifications, and its meaning for the implementation …
epigenome, the entirety of epigenetic modifications, and its meaning for the implementation …
Next‐generation technologies and data analytical approaches for epigenomics
Epigenetics refers to the collection of heritable features that modulate the genome–
environment interaction without being encoded in the actual DNA sequence. While being …
environment interaction without being encoded in the actual DNA sequence. While being …
Principles and challenges of genome-wide DNA methylation analysis
PW Laird - Nature Reviews Genetics, 2010 - nature.com
Methylation of cytosine bases in DNA provides a layer of epigenetic control in many
eukaryotes that has important implications for normal biology and disease. Therefore …
eukaryotes that has important implications for normal biology and disease. Therefore …
Methods in DNA methylation profiling
Metastable and somatically heritable patterns of DNA methylation provide an important level
of genomic regulation. In this article, we review methods for analyzing these genome-wide …
of genomic regulation. In this article, we review methods for analyzing these genome-wide …
[HTML][HTML] Epigenetic changes in cancer
M Esteller - F1000 biology reports, 2011 - ncbi.nlm.nih.gov
Interest in epigenetics is now booming in all the biomedical fields. Initially, interest was
sparked within the field of cancer research with the finding of global DNA hypomethylation …
sparked within the field of cancer research with the finding of global DNA hypomethylation …
Epigenomics: genome-wide study of methylation phenomena
KL Novik, I Nimmrich, B Genc, S Maier… - Current issues in …, 2002 - mdpi.com
Epigenetics is one of the key areas of future research that can elucidate how genomes work.
It combines genetics and the environment to address complex biological systems such as …
It combines genetics and the environment to address complex biological systems such as …