Alkaloid-derived pharmaceuticals are commonly semisynthesized from plant-extracted
starting materials, which often limits their availability and final price. Recent advances in …

Plants produce some of the most potent therapeutics and have been used for thousands of
years to treat human diseases. Today, many medicinal natural products are still extracted …

Numerous drugs and drug precursors in the current pharmacopoeia originate from plant
sources. The limited yield of some bioactive compounds in plant tissues, however, presents …

Higher plants produce diverse chemicals, including alkaloids, terpenoids, and phenolic
compounds (phenylpropanoids and flavonoids) as secondary metabolites. These chemicals …

Alkaloids continue to provide mankind with a plethora of medicines, poisons and potions.
Because many valuable drugs are derived from such natural compounds, there is much …

Natural products continue to provide privileged scaffolds for drug discovery. However,
challenges in supply and structure diversification can limit development. Here, we discuss …

The secondary metabolites of higher plants include diverse chemicals, such as alkaloids,
isoprenoids and phenolic compounds (phenylpropanoids and flavonoids). Although these …

Plant natural products have been extensively exploited in food, medicine, flavor, cosmetic,
renewable fuel, and other industrial sectors. Synthetic biology has recently emerged as a …

Plant natural products (PNPs) and their derivatives are important but underexplored sources
of pharmaceutical molecules. To access this untapped potential, the reconstitution of …

Medicinal plants are rich in secondary metabolites with beneficial pharmacological effects.
The production of plant secondary metabolites is subjected to the influences by …