This study proposes a 3D particle-based (discrete) multiphysics approach for modelling
calcification in the aortic valve. Different stages of calcification (from mild to severe) were …

Calcific aortic valve disease (CAVD) is characterized by calcification accumulation and
thickening of the aortic valve cusps, leading to stenosis. The importance of fluid flow shear …

We propose a mesh-free and discrete (particle-based) multi-physics approach for modelling
the hydrodynamics in flexible biological valves. In the first part of this study, the method is …

Cardiovascular system diseases, as aortic valve stenosis, are the main cause of mortality
and morbidity among patients. There is still a room for enhancement of the diagnostic and …

Calcific aortic valve disease is a common cause of aortic stenosis, a life threatening
condition. In this study, a mathematical model is developed to simulate the cascade of …

Calcific aortic valve disease (CAVD) is a common cardiovascular disease that affects
millions of people worldwide. The disease is characterized by the formation of calcium …

Patients with bicuspid aortic valve (BAV) are more likely to develop a calcific aortic stenosis
(CAS), as well as a number of other ailments, as compared to their cohorts with normal …

Background and objective Coronary artery diseases and aortic valve stenosis are two of the
main causes of mortality and morbidity worldwide. Stenosis of the aortic valve develops due …

Calcified aortic valve stenosis (CAVS) is caused by calcium buildup and tissue thickening
that impede the blood flow from left ventricle (LV) to aorta. In recent years, CAVS has …

Different hemodynamic characteristics of the blood flow can be studied by numerical
simulations of the blood flow around the heart valves, which are significantly useful in …