[PDF][PDF] Immunoglobulin M: a neglected serum biomarker in treatment‐naive primary biliary cholangitis with normal alkaline phosphatase

D Ding, G Xuan, Y Hu, J Yu, Y Liu… - Hepatology …, 2022 - Wiley Online Library
The diagnosis of primary biliary cholangitis (PBC) in patients with seropositive anti‐
mitochondrial antibody (AMA) but normal alkaline phosphatase (ALP) depends on a liver …

Positive antimitochondrial antibody but normal serum alkaline phosphatase levels: Could it be primary biliary cholangitis?

T Berdichevski, O Cohen‐Ezra, O Pappo… - Hepatology …, 2017 - Wiley Online Library
Aim Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease, typically
diagnosed by elevated cholestatic liver enzymes and a positive antimitochondrial antibody …

The diagnostic accuracy of biomarkers for diagnosis of primary biliary cholangitis (PBC) in anti-mitochondrial antibody (AMA)-negative PBC patients: a review of …

F de Liso, C Matinato, M Ronchi… - Clinical Chemistry and …, 2017 - degruyter.com
Primary biliary cholangitis (PBC), also known as primary biliary cirrhosis, is an autoimmune
disease of the liver characterized by anti-mitochondrial antibodies (AMA) in 90%–95% of …

[HTML][HTML] Diagnostic value of anti-mitochondrial antibody in patients with primary biliary cholangitis: A systemic review and meta-analysis

Q Xu, W Zhu, Y Yin - Medicine, 2023 - journals.lww.com
Background: Anti-mitochondrial antibodies (AMA) and the M2 subtype are considered
serological hallmarks in the diagnosis of primary biliary cholangitis (PBC). However, these …

Primary biliary cholangitis with normal alkaline phosphatase: a neglected clinical entity challenging current guidelines

BT Beretta-Piccoli, G Stirnimann, J Mertens… - Journal of …, 2021 - Elsevier
Background & aim The diagnosis of primary biliary cholangitis (PBC), an uncommon
immune-mediated cholestatic liver disease, is based on positive circulating anti …

[PDF][PDF] The future risk of primary biliary cholangitis (PBC) is low among patients with incidental anti‐mitochondrial antibodies but without baseline PBC

W Duan, S Chen, S Li, T Lv, B Li… - Hepatology …, 2022 - Wiley Online Library
Anti‐mitochondrial autoantibodies (AMAs) are highly specific for the diagnosis of primary
biliary cholangitis (PBC) but are also occasionally found in other diseases. In the present …

Anti-mitochondrial antibody-negative primary biliary cholangitis is part of the same spectrum of classical primary biliary cholangitis

GGL Cançado, MH Braga, MLG Ferraz… - Digestive diseases and …, 2021 - Springer
Background Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease in which
anti-mitochondrial antibodies (AMA) are the diagnostic hallmark. Whether AMA-negative …

Similar clinical outcome of AMA immunoblot-M2-negative compared to immunoblot-positive subjects over six years of follow-up

S Zandanell, M Strasser, A Feldman… - Postgraduate …, 2021 - Taylor & Francis
Background: The detection of anti-mitochondrial antibodies (AMA) is considered a hallmark
in diagnosing primary biliary cholangitis (PBC). The most important AMA-subtype is AMA-M2 …

Presence of anti-gp210 or anti-sp100 antibodies in AMA-positive patients may help support a diagnosis of primary biliary cholangitis

TD Jaskowski, V Nandakumar, CL Novis, M Palmer… - Clinica Chimica …, 2023 - Elsevier
Background Anti-mitochondrial antibody (AMA) positivity is not always associated with
primary biliary cholangitis (PBC). We aimed to determine the additional value of anti-sp100 …

Low rate of new‐onset primary biliary cholangitis in a cohort of anti‐mitochondrial antibody‐positive subjects over six years of follow‐up

S Zandanell, M Strasser, A Feldman… - Journal of Internal …, 2020 - Wiley Online Library
Abstract Background and Aims Anti‐mitochondrial antibodies (AMA) are closely linked to
primary biliary cholangitis (PBC). The prevalence of AMA in the general population is low …