Reproduction is controlled by the hypothalamic-pituitary-gonadal (HPG) axis. Gonadotropin-
releasing hormone (GnRH) neurons play a central role in this axis through production of …

The hypothalamic–pituitary–gonadal axis (HPG) plays vital roles in reproduction and steroid
hormone production in both sexes. The focus of this review is upon gene structures, receptor …

Evolutionary survival of a species is largely a function of its reproductive fitness. In
mammals, a sparsely populated and widely dispersed network of hypothalamic neurons, the …

Pulsatile secretion of the hypothalamic decapeptide gonadotrophin-releasing hormone
(GnRH) regulates activity of the pituitary–gonadal reproductive axis. Defects of this …

Puberty is a complex process that culminates in the acquisition of psychophysical maturity
and reproductive capacity. This elaborate and fascinating process marks the end of …

Gonadotropin releasing hormone (GnRH) neurons originate the nasal placode and migrate
into the brain during prenatal development. Once within the brain, these cells become …

The development of Gonadotropin releasing hormone-1 (GnRH) neurons is important for a
functional reproduction system in vertebrates. Disruption of GnRH results in hypogonadism …

A century of research has shown that in rodents, as in higher mammals, puberty is initiated
by the activation of the hypothalamic–pituitary–gonadal axis, and specifically, by the release …

Gonadotropin Releasing Hormone (GnRH) is a key regulator of reproduction and sexual
behaviour. During the last decade, embryological studies have clarified the question of the …

Human puberty is triggered by the reemergence of GnRH pulsatile secretion, with
progressive activation of gonadal function. Several mutations have been identified in an …