Engineering nanosystems for ROS-bridged cancer cascade therapy

Q Fu, L Yu, M Zhang, S Li, L Liu - Chemical Engineering Journal, 2023 - Elsevier
Developing efficient cancer treatment modalities is crucial, given the tens of thousands of
deaths that cancer causes each year. Although there are various treatment modalities …

Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy

Z Zhou, J Song, L Nie, X Chen - Chemical society reviews, 2016 - pubs.rsc.org
The reactive oxygen species (ROS)-mediated mechanism is the major cause underlying the
efficacy of photodynamic therapy (PDT). The PDT procedure is based on the cascade of …

Recent progress in the augmentation of reactive species with nanoplatforms for cancer therapy

M Wu, Y Ding, L Li - Nanoscale, 2019 - pubs.rsc.org
Reactive species (RS), mainly including reactive oxygen species (ROS) and reactive
nitrogen species (RNS), are indispensable in a wide variety of biological processes. RS …

A Photo‐Activated Continuous Reactive Oxygen Species Nanoamplifier for Dual‐Dynamic Cascade Cancer Therapy

X Zhang, X Zhang, H Guo, S Jia, Y Li… - Advanced …, 2023 - Wiley Online Library
The special redox homeostasis of tumor cells makes reactive oxygen species (ROS)‐based
approaches a promising cancer therapeutic strategy. Among these approaches …

Nanoplatform-based cascade engineering for cancer therapy

J Chen, Y Zhu, C Wu, J Shi - Chemical Society Reviews, 2020 - pubs.rsc.org
Various therapeutic techniques have been studied for treating cancer precisely and
effectively, such as targeted drug delivery, phototherapy, tumor-specific catalytic therapy …

Stimuli‐activatable nanomedicines for chemodynamic therapy of cancer

W Wang, Y Jin, Z Xu, X Liu, SZ Bajwa… - Wiley …, 2020 - Wiley Online Library
Chemodynamic therapy (CDT) takes the advantages of Fenton‐type reactions triggered by
endogenous chemical energy to generate highly cytotoxic hydroxyl radicals. As a novel …

Nano-ROS-generating approaches to cancer dynamic therapy: lessons from nanoparticles

Q Zhang, Q Luo, Z Liu, M Sun, X Dong - Chemical Engineering Journal, 2023 - Elsevier
Reactive oxygen species (ROS)-based dynamic cancer therapies are therapeutic modalities
of endogenous/exogenous-responsive intratumoral ROS generation, including …

Nanomedicines for reactive oxygen species mediated approach: an emerging paradigm for cancer treatment

S Kwon, H Ko, DG You, K Kataoka… - Accounts of Chemical …, 2019 - ACS Publications
Conspectus Growth in the knowledge of cancer biology has led to the emergence and
evolution of cancer nanomedicines by providing the rationale for leveraging nanotechnology …

Tumor metabolism‐engineered composite nanoplatforms potentiate sonodynamic therapy via reshaping tumor microenvironment and facilitating electron–hole pairs' …

X Guan, HH Yin, XH Xu, G Xu, Y Zhang… - Advanced Functional …, 2020 - Wiley Online Library
Reactive oxygen species (ROS) depletion and low ROS production that result from the
intratumoral redox metabolism equilibrium and low energy conversion efficiency from …

Nanosystems for chemodynamic based combination therapy: Strategies and recent advances

M Li, W Zhang, X Xu, G Liu, M Dong, K Sun… - Frontiers in …, 2022 - frontiersin.org
Chemodynamic therapy (CDT), a newly developed approach for cancer treatment, can
convert hydrogen peroxide (H2O2) into toxic hydroxyl radicals (• OH) by using …