Rho GTPases are signalling molecules regulating morphology and multiple cellular
functions including metabolism and vesicular trafficking. To understand the connection …

Summary Cdc42/Rho GTPases are universally important regulators of cellular
morphogenesis. Whereas their functions are well characterized in budding yeast, they are …

RacA is the main Rho GTPase in Aspergillus niger regulating polarity maintenance via
controlling actin dynamics. Both deletion and dominant activation of RacA (RacG18V) …

Rho proteins are key regulators of cellular morphogenesis, but their function in filamentous
fungi is poorly understood. By generating conditional rho‐1 mutants, we dissected the …

In filamentous fungi, growth and protein secretion occurs predominantly at the tip of long,
thread like cells termed hyphae. This requires coordinated regulation of multiple processes …

Farnesol is known for inducing apoptosis in some fungi and mammalian cells. To evaluate
its potential role as an antifungal agent, we studied its impact on the human pathogen …

Growth of the filamentous fungus Aspergillus nidulans begins when the conidium breaks
dormancy and grows isotropically. Eventually a germ tube emerges and the axis of growth …

The fungal kingdom is extremely diverse–comprised of over 1.5 million species including
yeasts, molds and mushrooms. Essentially, all fungi have cell walls that contain chitin and …

Polarized cell growth requires a polarized organization of the actin cytoskeleton. Small GTP-
binding proteins of the Rho-family have been shown to be involved in the regulation of actin …

Proteins in the Rho family are small monomeric GTPases primarily involved in polarization,
control of cell division, and reorganization of cytoskeletal elements. Phylogenetic analysis of …