Polyelectrolytes such as polyaspartic acid (PAsp) are critical in biomimetic mineralization as
stabilizers of amorphous calcium phosphate (ACP) precursors and as nucleation inhibitors …

The significant role of the polyelectrolytic nature of non-collagenous proteins (NCPs) in
regulating the in vivo mineralization of collagen provides important insights for scientists …

Inspired by nature, poly (acrylic acid)(PAA) and other polyelectrolytes have been used as
noncollagenous proteins (NCPs) surrogates for biomimetic intrafibrillar mineralization of …

Although “chaperone molecules” rich in negatively charged residues (ie, glutamic and
aspartic acid) are known to play important roles in the biomineralization process, the precise …

We revealed that nucleation sites within collagen fibrils determined pathways for calcium
phosphate (CaP) nucleation and its transformation, from amorphous species to crystalline …

The critical role of the self-assembled structure of collagen in skeletal mineralization is long
recognized, yet the angstrom to tens of nanometers length-scale nucleation mechanism of …

Biomimetic mineralization of collagen fibrils is an essential process because the mineralized
collagen fibers constitute the basic building block of natural bone. To overcome the limited …

Crosslinked gelatin films with entrapped poly‐L‐aspartate were used to induce the
crystallization of calcite and aragonite polymorphs. Calcite with high degrees of …

Bone is a hierarchically structured composite material whose basic building block is the
mineralized collagen fibril, where the collagen is the scaffold into which the hydroxyapatite …

Collagen biomineralization is regulated by complicated interactions between the collagen
matrix and non-collagenous extracellular proteins. Here, the use of sodium tripolyphosphate …