Single-cell RNA sequencing (scRNA-seq) enables specific profiling of cell populations at
single-cell resolution. The osteoimmunology microenvironment in the occurrence and …

Periodontitis involves the loss of connective tissue attachment and alveolar bone. Single cell
RNA-seq experiments have provided new insight into how resident cells and infiltrating …

Periodontitis is a highly prevalent chronic inflammatory disease leading to periodontal tissue
breakdown and subsequent tooth loss, in which excessive host immune response accounts …

Periodontitis is the sixth most common chronic inflammatory disease, destroying the tissues
supporting the teeth. There are three distinct stages in periodontitis: infection, inflammation …

Background Host immunity plays an important role against oral microorganisms in
periodontitis. Methods This study assessed the infiltrating immune cell subtypes in 133 …

Periodontitis is a highly prevalent chronic inflammatory disease of the periodontium, leading
ultimately to tooth loss. In order to characterize the gene expression of periodontitis-affected …

Aim Osteoimmunology covers the cellular and molecular mechanisms responsible for
inflammatory osteolysis that culminates in the degradation of alveolar bone …

Background Periodontitis is a polymicrobial biofilm-induced inflammatory disease that
affects 743 million people worldwide. The current model to explain periodontitis progression …

The oral mucosa remains an understudied barrier tissue. This is a site of rich exposure to
antigens and commensals, and a tissue susceptible to one of the most prevalent human …

The alveolar bone resorption is a distinctive feature of periodontitis progression and
determinant for tooth loss. Regulatory T lymphocytes (Tregs) display immuno-suppressive …