Mitochondria are membrane-bound cellular organelles of high relevance responsible for the
chemical energy production used in most of the biochemical reactions of cells. Mitochondria …

Mitochondrial genetics has become an emerging area of research in the field of modern
therapeutics. Mitochondrial genome is the source of 13 polypeptides which are components …

Mitochondrial gene therapy seems to be a valuable and promising strategy to treat
mitochondrial disorders. The use of a therapeutic vector based on mitochondrial DNA, along …

Many “classic” mitochondrial diseases have been described that arise from single
homoplasmic mutations in mitochondrial DNA (mtDNA). These diseases typically affect …

Mitochondria play an essential role in cellular metabolism and generate energy in cells. To
support these functions, several proteins are encoded in the mitochondrial DNA (mtDNA) …

Mitochondria carry out various essential functions including ATP production, the regulation
of apoptosis and possess their own genome (mtDNA). Delivering target molecules to this …

The field of mitochondrial research is currently among the fastest growing disciplines in
biomedicine. Approximately 12,000 articles on mitochondria have been published since the …

Mitochondrial dysfunction causes or contributes to a large number of human disorders
including neuromuscular and neurodegenerative diseases, diabetes, ischaemia …

Mitochondrial genome (mtDNA) independent of nuclear gene is a set of double-stranded
circular DNA that encodes 13 proteins, 2 ribosomal RNAs and 22 mitochondrial transfer …

Introduction: Research has revealed a relationship between mitochondrial dysfunction and
diseases such as diabetes, ischemia–reperfusion injury, cancer and many more. As a result …