Cholesterol metabolism: a new molecular switch to control inflammation
D Cardoso, E Perucha - Clinical Science, 2021 - portlandpress.com
The immune system protects the body against harm by inducing inflammation. During the
immune response, cells of the immune system get activated, divided and differentiated in …
immune response, cells of the immune system get activated, divided and differentiated in …
Immunometabolic function of cholesterol in cardiovascular disease and beyond
L Yvan-Charvet, F Bonacina… - Cardiovascular …, 2019 - academic.oup.com
Inflammation represents the driving feature of many diseases, including atherosclerosis,
cancer, autoimmunity and infections. It is now established that metabolic processes shape a …
cancer, autoimmunity and infections. It is now established that metabolic processes shape a …
The cholesterol pathway: impact on immunity and cancer
RJ King, PK Singh, K Mehla - Trends in immunology, 2022 - cell.com
Cholesterol is a multifaceted metabolite that is known to modulate processes in cancer,
atherosclerosis, and autoimmunity. A common denominator between these diseases …
atherosclerosis, and autoimmunity. A common denominator between these diseases …
Impact of cholesterol metabolism in immune cell function and atherosclerosis
M Aguilar-Ballester, A Herrero-Cervera, Á Vinué… - Nutrients, 2020 - mdpi.com
Cholesterol, the most important sterol in mammals, helps maintain plasma membrane fluidity
and is a precursor of bile acids, oxysterols, and steroid hormones. Cholesterol in the body is …
and is a precursor of bile acids, oxysterols, and steroid hormones. Cholesterol in the body is …
Lipid metabolism in inflammation-related diseases
C Zhang, K Wang, L Yang, R Liu, Y Chu, X Qin, P Yang… - Analyst, 2018 - pubs.rsc.org
There are thousands of lipid species existing in cells, which belong to eight different
categories. Lipids are the essential building blocks of cells. Recent studies have started to …
categories. Lipids are the essential building blocks of cells. Recent studies have started to …
Regulation of adaptive immunity in health and disease by cholesterol metabolism
MB Fessler - Current allergy and asthma reports, 2015 - Springer
Four decades ago, it was observed that stimulation of T cells induces rapid changes in
cellular cholesterol that are required before proliferation can commence. Investigators …
cellular cholesterol that are required before proliferation can commence. Investigators …
Role of lipids in the metabolism and activation of immune cells
MJ Hubler, AJ Kennedy - The Journal of nutritional biochemistry, 2016 - Elsevier
Immune cell plasticity has extensive implications in the pathogenesis and resolution of
metabolic disorders, cancers, autoimmune diseases and chronic inflammatory disorders …
metabolic disorders, cancers, autoimmune diseases and chronic inflammatory disorders …
The role of signalling in cellular cholesterol homeostasis
Cholesterol is a vital lipid and performs diverse functions on a whole body and cellular level.
However, excess cellular cholesterol is toxic, and thus, elegant mechanisms have evolved to …
However, excess cellular cholesterol is toxic, and thus, elegant mechanisms have evolved to …
[HTML][HTML] Diverse immunoregulatory roles of oxysterols—the oxidized cholesterol metabolites
C Choi, DK Finlay - Metabolites, 2020 - mdpi.com
Intermediates of both cholesterol synthesis and cholesterol metabolism can have diverse
roles in the control of cellular processes that go beyond the control of cholesterol …
roles in the control of cellular processes that go beyond the control of cholesterol …
The intracellular cholesterol landscape: dynamic integrator of the immune response
MB Fessler - Trends in immunology, 2016 - cell.com
Cholesterol has typically been considered an exogenous, disease-related factor in
immunity; however, recent literature suggests that a paradigm shift is in order. Sterols are …
immunity; however, recent literature suggests that a paradigm shift is in order. Sterols are …