Reduced-intensity conditioning (RIC) has offered many primary immunodeficiency disorder
(PID) patients who are ineligible for myeloablative regimens a chance of cure. However, the …

Background Reduced-intensity conditioning (RIC) regimens are increasingly being used in
the transplantation of patients with primary immunodeficiency disorders (PIDs), but there are …

Conventional myeloablative conditioning regimens prior to hematopoietic cell
transplantation (HCT) are associated with significant transplant-related morbidity and …

Purpose The purpose of our study was to compare the safety and efficacy of hematopoietic
cell transplantation (HCT) using fludarabine (Flu)-based reduced intensity conditioning …

The optimal approach to stem cell transplantation in children with immunodeficiency who
lack a matched family donor is controversial. Unrelated donor stem cell transplantation gives …

It is more than 40 years since the first successful hematopoietic cell transplants (HCT) were
reported in children with primary immunodeficiency disorders (PID). 1, 2 Many advances …

Studies so far indicate that reduced intensity transplantation (RIT) may have an important
role in treating patients with primary immunodeficiency disease (PID). Unlike more standard …

Primary immunodeficiencies (PID) are heterogeneous inborn errors of the immune system.
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is curative and safe at the …

The optimal preparation for stem cell transplantation (SCT) in children with congenital
immunodeficiencies is currently unknown. In all, 81 children with immunodeficiency …

The optimal approach for stem cell transplantation in children with immunodeficiency has yet
to be determined. Conditioning therapy is necessary for reliable engraftment and full …