Atherosclerosis is the principal cause of cardiovascular disease that continues to be a
substantial drain on healthcare systems, being responsible for about 31% of all global …

Atherosclerosis is still one of the main causes of death around the globe. This condition
leads to various life-threatening cardiovascular complications. However, no effective …

Atherosclerosis is a chronic, inflammatory disease of the arterial wall that underlies many of
the common causes of cardiovascular morbidity and mortality, including myocardial …

The limited efficacy of current treatment strategies for targeting atherosclerosis and its
complications requires new therapeutic options to be explored. From early fatty-streak …

Atherosclerosis is a lipid-driven inflammatory disease of the arterial intima in which the
balance of pro-inflammatory and inflammation-resolving mechanisms dictates the final …

Introduction Lipid-laden foam cells within atherosclerotic plaques are key players in all
phases of lesion development including its progression, necrotic core formation, fibrous cap …

Atherosclerosis is characterized by chronic inflammation of the vascular wall. Macrophages,
which differentiate from circulating monocytes, give rise to foam cells by excessive …

Cardiovascular disease is the biggest killer globally and the principal contributing factor to
the pathology is atherosclerosis; a chronic, inflammatory disorder characterized by lipid and …

Atherosclerosis is the narrowing of arteries due to the accumulation of macrophages
overloaded with lipids resulting in foam cell formation, and these events occur preferentially …

Monocytes and their descendant macrophages are essential to the development and
exacerbation of atherosclerosis, a lipid-driven inflammatory disease. Lipid-laden …