Brown adipocyte glucose metabolism: a heated subject
MK Hankir, M Klingenspor - EMBO reports, 2018 - embopress.org
The energy expending and glucose sink properties of brown adipose tissue (BAT) make it
an attractive target for new obesity and diabetes treatments. Despite decades of research …
an attractive target for new obesity and diabetes treatments. Despite decades of research …
Brown adipose tissue—a translational perspective
AC Carpentier, DP Blondin, F Haman… - Endocrine …, 2023 - academic.oup.com
Brown adipose tissue (BAT) displays the unique capacity to generate heat through
uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for …
uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for …
Brown fat fuel utilization and thermogenesis
KL Townsend, YH Tseng - Trends in Endocrinology & Metabolism, 2014 - cell.com
Brown adipose tissue (BAT) dissipates energy as heat to maintain optimal thermogenesis
and to contribute to energy expenditure in rodents and possibly humans. The energetic …
and to contribute to energy expenditure in rodents and possibly humans. The energetic …
[HTML][HTML] Substrate utilization by brown adipose tissue: what's hot and what's not?
BT McNeill, NM Morton, RH Stimson - Frontiers in endocrinology, 2020 - frontiersin.org
Our understanding of brown adipose tissue (BAT) function in humans has increased rapidly
over the past 10 years. This is predominantly due to the development of powerful non …
over the past 10 years. This is predominantly due to the development of powerful non …
Neuronal control of brown fat activity
S Kooijman, JK van den Heuvel… - Trends in Endocrinology & …, 2015 - cell.com
Brown adipose tissue (BAT) activation reduces body fat and metabolic disorders by the
enhanced combustion of lipids and glucose into heat. The thermogenic activity of brown …
enhanced combustion of lipids and glucose into heat. The thermogenic activity of brown …
Using brown adipose tissue to treat obesity–the central issue
Current therapeutic strategies are proving inadequate to deal with growing obesity rates
because of the inherent resistance of the human body to weight loss. The activation of …
because of the inherent resistance of the human body to weight loss. The activation of …
[HTML][HTML] Mechanisms of impaired brown adipose tissue recruitment in obesity
M Alcalá, M Calderon-Dominguez, D Serra… - Frontiers in …, 2019 - frontiersin.org
Brown adipose tissue (BAT) dissipates energy to produce heat. Thus, it has the potential to
regulate body temperature by thermogenesis. For the last decade, BAT has been in the …
regulate body temperature by thermogenesis. For the last decade, BAT has been in the …
[HTML][HTML] Brown adipose tissue heterogeneity, energy metabolism, and beyond
Brown adipocyte in brown adipose tissue (BAT) specializes in expending energy through
non-shivering thermogenesis, a process that produces heat either by uncoupling protein 1 …
non-shivering thermogenesis, a process that produces heat either by uncoupling protein 1 …
[HTML][HTML] Studying Brown Adipose Tissue in a Human in vitro Context
I Samuelson, A Vidal-Puig - Frontiers in endocrinology, 2020 - frontiersin.org
New treatments for obesity and associated metabolic disease are increasingly warranted
with the growth of the obesity pandemic. Brown adipose tissue (BAT) may represent a …
with the growth of the obesity pandemic. Brown adipose tissue (BAT) may represent a …
The evolving view of thermogenic adipocytes—ontogeny, niche and function
The worldwide incidence of obesity and its sequelae, such as type 2 diabetes mellitus, have
reached pandemic levels. Central to the development of these metabolic disorders is …
reached pandemic levels. Central to the development of these metabolic disorders is …