Quantitative mass spectrometry reveals food intake-induced neuropeptide level changes in rat brain: functional assessment of selected neuropeptides as feeding …

H Ye, J Wang, Z Tian, F Ma, J Dowell, Q Bremer… - Molecular & Cellular …, 2017 - ASBMB
Endogenous neuropeptides are important signaling molecules that function as regulators of
food intake and body weight. Previous work has shown that neuropeptide gene expression …

Profiling of diet-induced neuropeptide changes in rat brain by quantitative mass spectrometry

CK Frese, AJ Boender, S Mohammed… - Analytical …, 2013 - ACS Publications
Neuropeptides are intercellular signal transmitters that play key roles in modulation of many
behavioral and physiological processes. Neuropeptide signaling in several nuclei in the …

Comparative neuropeptidomic analysis of food intake via a multifaceted mass spectrometric approach

R Chen, L Hui, SS Cape, J Wang… - ACS chemical …, 2010 - ACS Publications
Feeding behavior is a fundamental aspect of energy homeostasis and is crucial for animal
survival. This process is regulated by a multitude of neurotransmitters including …

ProSAAS-derived peptides are colocalized with neuropeptide Y and function as neuropeptides in the regulation of food intake

JH Wardman, I Berezniuk, S Di, JG Tasker, LD Fricker - PloS one, 2011 - journals.plos.org
ProSAAS is the precursor of a number of peptides that have been proposed to function as
neuropeptides. Because proSAAS mRNA is highly expressed in the arcuate nucleus of the …

Data-independent MS/MS quantification of neuropeptides for determination of putative feeding-related neurohormones in microdialysate

CM Schmerberg, Z Liang, L Li - Acs Chemical Neuroscience, 2015 - ACS Publications
Food consumption is an important behavior that is regulated by an intricate array of
neuropeptides (NPs). Although many feeding-related NPs have been identified in mammals …

Integrated label-free and 10-plex dileu isobaric tag quantitative methods for profiling changes in the mouse hypothalamic neuropeptidome and proteome: Assessment …

R Liu, P Wei, C Keller, NS Orefice, Y Shi, Z Li… - Analytical …, 2020 - ACS Publications
Gut microbiota can regulate host physiological and pathological status through gut–brain
communications or pathways. However, the impact of the gut microbiome on neuropeptides …

Diet-induced neuropeptide expression: feasibility of quantifying extended and highly charged endogenous peptide sequences by selected reaction monitoring

T Schmidlin, AJ Boender, CK Frese, AJR Heck… - Analytical …, 2015 - ACS Publications
Understanding regulation and action of endogenous peptides, especially neuropeptides,
which serve as inter-and intracellular signal transmitters, is key in understanding a variety of …

High identification rates of endogenous neuropeptides from mouse brain

X Zhang, F Petruzziello, F Zani, L Fouillen… - Journal of proteome …, 2012 - ACS Publications
Mass spectrometry-based neuropeptidomics is one of the most powerful approaches for
identification of endogenous neuropeptides in the brain. Until now, however, the …

[HTML][HTML] Neuropeptidomics: mass spectrometry-based identification and quantitation of neuropeptides

JE Lee - Genomics & informatics, 2016 - ncbi.nlm.nih.gov
Neuropeptides produced from prohormones by selective action of endopeptidases are vital
signaling molecules, playing a critical role in a variety of physiological processes, such as …

Neuropeptidomic components generated by proteomic functions in secretory vesicles for cell–cell communication

V Hook, S Bark, N Gupta, M Lortie, WD Lu, N Bandeira… - The AAPS journal, 2010 - Springer
Diverse neuropeptides participate in cell–cell communication to coordinate neuronal and
endocrine regulation of physiological processes in health and disease. Neuropeptides are …