Background: A substantial body of studies supports the view that molecular and cellular
features of endometriotic lesions differ from those of eutopic endometrium. Apart from that …

Endometriosis, defined as the presence of endometrial glandular and stromal cells outside
the uterine cavity, is a common gynecological disease with poorly understood pathogenesis …

According to a rich body of literature, immune cell dysfunctions, both locally and
systemically, and an inflammatory environment characterize all forms of endometriosis …

Members of the Wnt family of signaling molecules are important in cell specification and
epithelial-mesenchymal interactions, and targeted gene deletion of Wnt-7a in mice results in …

The theory of retrograde menstruation as aetiopathogenesis of endometriosis formulated by
John Sampson in 1927 shows clear shortcomings: this does not explain why retrograde …

STUDY HYPOTHESIS Do estrogen and Wnt/β-catenin signaling promote vascular
endothelial growth factor (VEGF) expression in endometriosis and how? STUDY FINDING …

Endometriosis is a common and painful condition affecting women of reproductive age.
While the underlying pathophysiology is still largely unknown, much advancement has been …

Endometriosis (EM) is characterized by the existence of endometrial mucosa outside the
uterine cavity, which causesinfertility, persistent aches, and a decline in women's quality of …

Endometriosis is a gynecological disease characterized by the presence of endometrial
glandular epithelial and stromal cells growing in the extra-uterine environment. The disease …

Endometriosis is a chronic gynecological disease, affecting up to 10% of reproductive-age
women. The exact cause of the disease is unknown; however, it is a heritable condition …