Identification and Properties of 1,119 Candidate LincRNA Loci in the Drosophila melanogaster Genome
RS Young, AC Marques, C Tibbit… - Genome biology and …, 2012 - academic.oup.com
The functional repertoire of long intergenic noncoding RNA (lincRNA) molecules has begun
to be elucidated in mammals. Determining the biological relevance and potential gene …
to be elucidated in mammals. Determining the biological relevance and potential gene …
[HTML][HTML] Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution
Thousands of long intervening noncoding RNAs (lincRNAs) have been identified in
mammals. To better understand the evolution and functions of these enigmatic RNAs, we …
mammals. To better understand the evolution and functions of these enigmatic RNAs, we …
[HTML][HTML] lincRNAs: genomics, evolution, and mechanisms
Long intervening noncoding RNAs (lincRNAs) are transcribed from thousands of loci in
mammalian genomes and might play widespread roles in gene regulation and other cellular …
mammalian genomes and might play widespread roles in gene regulation and other cellular …
The vast, conserved mammalian lincRNome
D Managadze, AE Lobkovsky, YI Wolf… - PLoS computational …, 2013 - journals.plos.org
We compare the sets of experimentally validated long intergenic non-coding (linc) RNAs
from human and mouse and apply a maximum likelihood approach to estimate the total …
from human and mouse and apply a maximum likelihood approach to estimate the total …
Genome-wide identification and developmental expression profiling of long noncoding RNAs during Drosophila metamorphosis
B Chen, Y Zhang, X Zhang, S Jia, S Chen, L Kang - Scientific reports, 2016 - nature.com
An increasing number of long noncoding RNAs (lncRNAs) have been discovered with the
recent advances in RNA-sequencing technologies. lncRNAs play key roles across diverse …
recent advances in RNA-sequencing technologies. lncRNAs play key roles across diverse …
Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs
Background Recent advances in transcriptome sequencing have enabled the discovery of
thousands of long non-coding RNAs (lncRNAs) across many species. Though several …
thousands of long non-coding RNAs (lncRNAs) across many species. Though several …
Conserved introns reveal novel transcripts in Drosophila melanogaster
Noncoding RNAs that are—like mRNAs—spliced, capped, and polyadenylated have
important functions in cellular processes. The inventory of these mRNA-like noncoding …
important functions in cellular processes. The inventory of these mRNA-like noncoding …
Comprehensive characterization of 10,571 mouse large intergenic noncoding RNAs from whole transcriptome sequencing
Large intergenic noncoding RNAs (lincRNAs) have been recognized in recent years to
constitute a significant portion of the mammalian transcriptome, yet their biological functions …
constitute a significant portion of the mammalian transcriptome, yet their biological functions …
Evolutionary dynamics and tissue specificity of human long noncoding RNAs in six mammals
Long intergenic noncoding RNAs (lincRNAs) play diverse regulatory roles in human
development and disease, but little is known about their evolutionary history and constraint …
development and disease, but little is known about their evolutionary history and constraint …
Epigenomic footprints across 111 reference epigenomes reveal tissue-specific epigenetic regulation of lincRNAs
Tissue-specific expression of lincRNAs suggests developmental and cell-type-specific
functions, yet tissue specificity was established for only a small fraction of lincRNAs. Here, by …
functions, yet tissue specificity was established for only a small fraction of lincRNAs. Here, by …