Background Emerging epidemiological evidence suggests that statin use may reduce the
risk of infections and infection-related complications. Our objective was to examine the …

Objective To evaluate whether the potential of statins to lower the risk of infections as
published in observational studies is causal. Design Systematic review and meta-analysis of …

Objective: Statins have pleiotropic effects that are independent of their lipid-lowering ability.
We have previously shown that prior statin therapy is associated with a decreased risk of …

PURPOSE: The aim of this study was to systematically review the literature on the effect of
statins on mortality in patients with infection and/or sepsis. MATERIALS AND METHODS …

Background Several studies have reported improved survival in severe bacterial infections
among statin treated patients. In addition, statins have been ascribed beneficial anti …

Introduction Statins are currently used for hyperlipidaemia control and considered useful for
protection from cardiovascular events. In addition, there is increasing evidence for the …

Rationale: In patients on prior statin therapy who are hospitalized for acute infections,
current literature is unclear on whether statins should be continued during their …

There is increasing discussion of a potential role for statins in the management of sepsis. A
search of PubMed, Embase, Scopus and the Cochrane Library databases was performed by …

Objectives: The objective was to investigate the association between statin therapy and
mortality in emergency department (ED) patients with suspected infection. Methods: A …

Background While some experimental and clinical research suggests that statins improve
outcomes after severe infections, the evidence for pneumonia is conflicting. We examined …