Polycystic ovary syndrome (PCOS) is an endocrine disorder and the main cause of
anovulatory infertility, in which persistent activation of androgen receptor (AR) due to …

Bromodomain (BRD)-containing proteins are evolutionarily conserved protein–protein
interaction modules involved in many biological processes. BRDs selectively recognize and …

Although chronic hyperandrogenism suppresses antral follicular development, a
phenomenon often observed in polycystic ovarian syndrome (PCOS), whether and how …

We previously observed high levels of Brd2 (also known as female sterile homeotic related
gene‐1, Fsrg1) expression in several hormonally responsive tissues, including the ovary …

Germ-line mutations in BRCA1 predispose women to early-onset, familial breast and
ovarian cancers. However, BRCA1 expression is not restricted to breast and ovarian …

Objective In humans, polycystic ovary syndrome (PCOS) is an androgen-dependent ovarian
disorder. Aberrant gene expression in folliculogenesis can arrest the transition of preantral …

High-grade serous ovarian carcinoma (HGSOC) is the most aggressive type of ovarian
cancer, often diagnosed at advanced stages. Molecularly, HGSOC shows high degree of …

Polycystic ovary syndrome (PCOS) is the leading cause of infertility in reproductive-age
women. Hyperandrogenism, polycystic ovaries, and chronic anovulation are its typical …

High-grade serous ovarian carcinoma (HGSOC) is the most common and aggressive form of
epithelial ovarian cancer, for which few targeted therapies exist. To search for new …

This study was to explore estrogen receptor (ER) involvement in FSH and TGFβ1-stimulated
steroidogenesis in rat ovarian granulosa cells. We first determined the specific involvement …