Angiotensin II elicits contractile responses in the coronary arteries and myocardial tissue,
which suggests that blockade of the renin-angiotensin system by specific agents should lead …

Systemic and coronary hemodynamic, metabolic and humoral effects of a new intravenous
angiotensin-convert-ing enzyme inhibitor, enalaprilat, were evaluated in 14 patients with …

Vasodilators may provoke myocardial ischemia in patients with coronary heart disease.
Therefore, we analyzed in conscious dogs the effect of angiotensin-converting enzyme …

BACKGROUND Cardiac hypertrophy is associated with elevated intracardiac angiotensin-
converting enzyme activity, which may contribute to diastolic dysfunction. METHODS AND …

The hemodynamic response 1 hour after 1.25 mg of intravenous (IV) enalaprilat was
examined in 20 patients (mean age 75 years) with severe congestive heart failure (CHF) …

To examine the manner in which changes in diastolic performance can contribute to the
effect of vasodilation in patients with left ventricular (LV) systolic dysfunction, we examined …

BACKGROUND There is increasing recognition of myocardial angiotensin-converting
enzyme, which is induced with the development of left ventricular hypertrophy (LVH). The …

The antihypertensive effect and tolerability of enalaprilat, an intravenously administered
angiotensin converting enzyme inhibitor, was studied in 65 patients with moderate or severe …

Renal and systemic hemodynamics were measured during titration of dopamine and serially
after intravenous administration of enalaprilat in nine patients with chronic severe …

Bradykinin accumulation is a potent cardioprotective mechanism underlying angiotensin-
converting enzyme (ACE) inhibition in ischemia and/or reperfusion injury. There is, however …