Identification of Key Genes for Pyroptosis-Induced Salivary Gland Inflammation in Sjogren's Syndrome Based on Microarray Data and Immunohistochemistry Analysis

K Zhang, Z Luo, X Zhu, X Yao, D Lu… - Journal of …, 2023 - Taylor & Francis
Purpose Sjogren's Syndrome (SS) is a systemic autoimmune disease primarily
characterized by dysfunction of the exocrine glands. Research into the etiology and …

Investigation of pyroptosis-related hub genes and the immune microenvironment in primary Sjögren's syndrome

W Chen, W Chen, N Xia, R Yan - Clinical and experimental … - pubmed.ncbi.nlm.nih.gov
Objectives Primary Sjögren's syndrome (pSS) is an inflammatory systemic autoimmune
disease, while the role and mechanisms of pyroptosis in pSS remain largely undefined …

CD4 T cell-secreted IFN-γ in Sjögren's syndrome induces salivary gland epithelial cell ferroptosis

J Zhou, JL Pathak, T Cao, B Chen, W Wei, S Hu… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Background Sjögren's syndrome (SS) is a chronic autoimmune disease that predominantly
affects exocrine glands. Previous studies have demonstrated that upregulated interferon …

[HTML][HTML] Identification of immunological characteristics and cuproptosis-related molecular clusters in primary Sjögren's syndrome

B Wei, A Wang, W Liu, Q Yue, Y Fan, B Xue… - International …, 2024 - Elsevier
Abstract Background Primary Sjögren's syndrome (pSS) is a chronic systemic autoimmune
disease characterized by lymphocyte infiltration of the exocrine glands. The typical clinical …

Integrative analysis of transcriptome and proteome in primary Sjögren syndrome

X Qiu, B Wang, H Gong, S Bu, P Li, R Zhao, M Li, L Zhu… - Genomics, 2024 - Elsevier
Abstract Objective Primary Sjögren's syndrome (pSS) is a intricate autoimmune disease
mainly characterized of immune-mediated destruction of exocrine tissues, such as salivary …

[HTML][HTML] Uncovering potential new biomarkers and immune infiltration characteristics in primary Sjögren's syndrome by integrated bioinformatics analysis

N Zhang, C Ji, X Bao, X Peng, M Tang, C Yuan - Medicine, 2023 - journals.lww.com
Primary Sjögren's syndrome (pSS) is known as autoimmune disease characterized by
damage to endocrine glands, such as the salivary and lacrimal glands. This study aimed to …

Integrated bioinformatics and validation reveal potential biomarkers associated with progression of primary Sjögren's syndrome

N Li, L Li, M Wu, Y Li, J Yang, Y Wu, H Xu… - Frontiers in …, 2021 - frontiersin.org
Background Primary Sjögren's syndrome (pSS) is a chronic systemic autoimmune disease
of the exocrine glands characterized by specific pathological features. Previous studies have …

Bioinformatics analysis for identification of key genes in salivary gland and the potential of a combination of biomarkers for the diagnosis of SS

L Chen, D Lu, K Yu, S He, L Liu, X Zhang… - Journal of …, 2021 - Taylor & Francis
Purpose Sjögren's syndrome (SS) is a systemic autoimmune disease mainly characterized
by dysfunction of exocrine glands. Studies on diagnosis models specific for SS patients are …

Identification of differentially expressed genes in primary Sjögren's syndrome

L Zhang, P Xu, X Wang, Z Zhang… - Journal of cellular …, 2019 - Wiley Online Library
Primary Sjögren's syndrome (pSS) is a chronic systemic autoimmune disease that affects
exocrine glands. To study the molecular mechanism and identify crucial genes/pathways in …

Proteomics analysis of tears and saliva from Sjogren's syndrome patients

N Das, NG Menon, LGN de Almeida… - Frontiers in …, 2021 - frontiersin.org
Sjogren's syndrome (SS) is characterized by dysfunctional mucous membranes and
dysregulated moisture-secreting glands resulting in various symptoms, including dry mouth …