5-Hydroxytryptamine (5-HT, serotonin) is a neurotransmitter in both the central nervous
system and peripheral structures, acting also as a hormone in platelets. Although its …

Abstract Serotonin (5-hydroxytryptamine or 5-HT) plays a critical physiological role in the
regulation of gastrointestinal (GI) function. 5-HT dysfunction may also be involved in the …

Serotonin (5-HT) is most commonly thought of as a neurotransmitter in the central nervous
system. However, the predominant site of serotonin synthesis, storage, and release is the …

The pharmacology of serotonin (5-hydroxytryptamine or 5-HT) in the gut has been the centre
of intense interest and research for several decades. Although it is now recognised that 5-HT …

Serotonin is an important gastrointestinal signaling molecule. It is a paracrine messenger
utilized by enterochromaffin (EC) cells, which function as sensory transducers. Serotonin …

Abstract Serotonin (5-hydroxytryptamine or 5-HT) once most extensively studied as a
neurotransmitter of the central nervous system, is seen to be predominantly secreted in the …

Abstract Serotonin (5-HT) has been recognized for decades as an important signalling
molecule in the gut, but it is still revealing its secrets. Novel gastrointestinal functions of 5-HT …

Abstract Serotonin (5‐hydroxytryptamine, 5‐HT) is present in abundance within the gut, most
stored in enterochromaffin cell granules. It is released by a range of stimuli, most potently by …

Serotonin, also known as 5-hydroxytryptamine (5-HT), is a metabolite of tryptophan and is
reported to modulate the development and neurogenesis of the enteric nervous system, gut …

Beside its role as a neurotransmitter in the central nervous system, serotonin appears to be
a central physiologic mediator of many gastrointestinal (GI) functions and a mediator of the …