Asthma is a chronic, complex and heterogeneous inflammatory illness, characterized by
obstruction of the lower airways. About 334 million people worldwide suffer from asthma …

Activation of mast cells and eosinophils is a fundamental process in the pathophysiology of
allergic diseases. We have previously reported that the novel enhydrazinone ester CEE-1 …

Allergic rhinitis (AR) is a nasal mucosal disease with sneezing and nasal itching as the main
symptoms. Although AR treatment continues to improve, there remains a lack of effective …

Objective AST2017-01 is developed to be used for treatment and prevention of allergic
diseases and composed of processed-Cordyceps militaris and processed-Rumex crispus …

Airway epithelial injury is the hallmark of various respiratory diseases and therapeutic
targeting of epithelial injury could be an effective strategy for controlling these diseases. We …

IPL576, 092, a lead compound from a novel class of polyhydroxylated sterols, was tested in
models of allergen-induced bronchoconstriction and airway inflammation. In a rat ovalbumin …

Abstract Introduction: Demethylzeylasteral (T-96), a new extract of Tripterygium wilfordii
Hook F, exerted immunomodulatory properties in autoimmune diseases, but its effect on …

Allergic inflammation and airway remodeling frequently occur in asthma. This study clarifies
a novel LINC1810064F22Rik-mediated ceRNA mechanism involved in asthma-induced …

RGFP966 is a selective inhibitor of histone deacetylase 3 (HDAC3) playing crucial roles in
triggering allergic and inflammatory responses. Whereas, its role in allergic rhinitis (AR) …

Background: Corticosteroids are the preferred option to treat asthma, however, they possess
serious side effects and are inefficient in 10% of patients. Thus, new therapeutic approaches …