The action of oxytocin on the bone of senescent female rats

LFG Santos, F Fernandes-Breitenbach, RAS Silva… - Life Sciences, 2022 - Elsevier
Aims This study verified the action of oxytocin (OT) as a preventive measure to control bone
damage during aging in female rats. Main methods Wistar rats received saline (0.15 …

[HTML][HTML] Protective effect of oxytocin against bone loss in a female rat model of osteoporosis

H Moghazy, AA Mahmoud, H Elbadre… - Reports of Biochemistry …, 2020 - ncbi.nlm.nih.gov
Background: Introduction: Oxytocin (OT) has been proposed to assist in the regulation of
bone remodeling and to exert an antiosteoporotic effect. We evaluated the possible …

Oxytocin and bone quality in the femoral neck of rats in periestropause

F Fernandes, CT Stringhetta-Garcia, MJ Peres-Ueno… - Scientific Reports, 2020 - nature.com
The objective of this study is to identify whether oxytocin (OT) contributes to the reduction of
osteopenia in the femoral neck of rats in periestropause. Animals in irregular estrous cycles …

[HTML][HTML] Oxytocin promotes bone formation during the alveolar healing process in old acyclic female rats

VC Colli, R Okamoto, PM Spritzer… - Archives of oral biology, 2012 - Elsevier
OBJECTIVE: OT was reported to be a direct regulator of bone mass in young rodents, and
this anabolic effect on bone is a peripheral action of OT. The goal of this study was to …

Oxytocin effects on osteoblastic differentiation of bone marrow mesenchymal stem cells from adult and aging female Wistar rats

LF Santos, MP Singulani, CT Stringhetta-Garcia… - Experimental …, 2018 - Elsevier
Recently, it has been suggested that oxytocin (OT) might play a role in the control of bone
remodeling and in bone health of young and adult females. The purpose of this study was to …

[PDF][PDF] Possible neuroendocrine role for oxytocin in bone remodeling

SK Elabd, I Sabry, WB Hassan, H Nour… - Endocrine …, 2007 - researchgate.net
Objective. The present study was carried out to evaluate the assumption that oxytocin (OT)
plays a neuroendocrine role in bone remodeling. For this purpose the changes in serum …

The mechanism of oxytocin and its receptors in regulating cells in bone metabolism

L Feixiang, F Yanchen, L Xiang, Z Yunke… - Frontiers in …, 2023 - frontiersin.org
Oxytocin (OT) is a neuropeptide known to affect social behavior and cognition. The
epigenetic modification of the oxytocin receptor (OTR) via DNA methylation stimulates …

Analysis of the femoral neck from rats in the periestropause treated with oxytocin and submitted to strength training

F Fernandes-Breitenbach, MJ Peres-Ueno, LFG Santos… - Bone, 2022 - Elsevier
Among the interventions used to prevent osteoporosis in female organisms, strength training
(ST) and oxytocin (OT) stand out, as a promising hormone with anabolic action on bone …

Oxytocin reverses osteoporosis in a sex-dependent manner

GE Beranger, M Djedaini, S Battaglia… - Frontiers in …, 2015 - frontiersin.org
The increase of life expectancy has led to the increase of age-related diseases such as
osteoporosis. Osteoporosis is characterized by bone weakening promoting the occurrence …

The effect of oxytocin on osseointegration of titanium implant in ovariectomized rats

M Wang, L Lan, T Li, J Li, Y Li - Connective Tissue Research, 2016 - Taylor & Francis
Introduction: Oxytocin (OT) was reported to control differentiation of human mesenchymal
stem cells and reverse osteoporosis (OP). This study investigated the effect of systematical …