Regulation of bacterial virulence by Csr (Rsm) systems
Most bacterial pathogens have the remarkable ability to flourish in the external environment
and in specialized host niches. This ability requires their metabolism, physiology, and …
and in specialized host niches. This ability requires their metabolism, physiology, and …
Post‐transcriptional regulation on a global scale: form and function of Csr/Rsm systems
T Romeo, CA Vakulskas… - Environmental …, 2013 - Wiley Online Library
Originally described as a repressor of gene expression in the stationary phase of growth,
CsrA (RsmA) regulates primary and secondary metabolic pathways, biofilm formation …
CsrA (RsmA) regulates primary and secondary metabolic pathways, biofilm formation …
An unusual CsrA family member operates in series with RsmA to amplify posttranscriptional responses in Pseudomonas aeruginosa
JN Marden, MR Diaz, WG Walton… - Proceedings of the …, 2013 - National Acad Sciences
Members of the CsrA family of prokaryotic mRNA-binding proteins alter the translation
and/or stability of transcripts needed for numerous global physiological processes. The …
and/or stability of transcripts needed for numerous global physiological processes. The …
[HTML][HTML] Structural rearrangement in an RsmA/CsrA ortholog of Pseudomonas aeruginosa creates a dimeric RNA-binding protein, RsmN
In bacteria, the highly conserved RsmA/CsrA family of RNA-binding proteins functions as
global posttranscriptional regulators acting on mRNA translation and stability. Through …
global posttranscriptional regulators acting on mRNA translation and stability. Through …
The post-transcriptional regulator CsrA plays a central role in the adaptation of bacterial pathogens to different stages of infection in animal hosts
C Lucchetti-Miganeh, E Burrowes, C Baysse… - …, 2008 - microbiologyresearch.org
The importance of Csr post-transcriptional systems is gradually emerging; these systems
control a variety of virulence-linked physiological traits in many pathogenic bacteria. This …
control a variety of virulence-linked physiological traits in many pathogenic bacteria. This …
Determination of the regulon and identification of novel mRNA targets of Pseudomonas aeruginosa RsmA
A Brencic, S Lory - Molecular microbiology, 2009 - Wiley Online Library
One of the prokaryotic post‐transcriptional regulatory mechanisms involves the CsrA/RsmA
family of proteins that act by modulating translation initiation at target mRNAs. In this study …
family of proteins that act by modulating translation initiation at target mRNAs. In this study …
Global regulation by CsrA and its RNA antagonists
T Romeo, P Babitzke - Microbiology spectrum, 2018 - Am Soc Microbiol
The sequence-specific RNA binding protein CsrA is employed by diverse bacteria in the
posttranscriptional regulation of gene expression. Its binding interactions with RNA have …
posttranscriptional regulation of gene expression. Its binding interactions with RNA have …
CsrB sRNA family: sequestration of RNA-binding regulatory proteins
P Babitzke, T Romeo - Current opinion in microbiology, 2007 - Elsevier
Noncoding regulatory RNA molecules, also known as small RNAs, participate in several
bacterial regulatory networks. The central component of the carbon storage regulator (Csr) …
bacterial regulatory networks. The central component of the carbon storage regulator (Csr) …
Global regulation by the small RNA‐binding protein CsrA and the non‐coding RNA molecule CsrB
T Romeo - Molecular microbiology, 1998 - Wiley Online Library
Csr (carbon storage regulator) is a recently discovered global regulatory system that controls
bacterial gene expression post‐transcriptionally. Its effector is a small RNA‐binding protein …
bacterial gene expression post‐transcriptionally. Its effector is a small RNA‐binding protein …
Post-transcriptional global regulation by CsrA in bacteria
J Timmermans, L Van Melderen - Cellular and molecular life sciences, 2010 - Springer
Global regulation allows bacteria to rapidly modulate the expression of a large variety of
unrelated genes in response to environmental changes. Global regulators act at different …
unrelated genes in response to environmental changes. Global regulators act at different …