Age-related decline in spatial navigation is well-known and the extant literature emphasizes
the important contributions of a hippocampus-dependent spatial navigation system in …

Spatial navigation is a complex cognitive skill that is necessary for everyday functioning in
the environment. However, navigational skills are not typically measured in most test …

Older adults have difficulties in navigating unfamiliar environments and updating their
wayfinding behavior when faced with blocked routes. This decline in navigational …

Age-related declines in spatial navigation are well-known in human and non-human
species. Studies in non-human species suggest that alteration in hippocampal and other …

Previous studies have showed that spatial memory declines with age but have not clarified
the relevance of different landmark cues for specifying heading directions among different …

Older age is associated with changes in the brain, including the medial temporal lobe, which
may result in mild spatial navigation deficits, especially in allocentric navigation. The aim of …

Cognitive deficits in normal aging have been associated with atrophy of the hippocampus.
As such, methods to detect early dysfunction of the hippocampus have become valuable, if …

Parizkova et al. investigated the potential role of hippocampal and basal forebrain volumes
in mediation of this interrelation. The results showed that lower hippocampal and basal …

Learning the spatial layout of a novel environment is associated with dynamic activity
changes in the hippocampus and in medial parietal areas. With advancing age, the ability to …

Retracing a recently traveled route is a frequent navigation task when learning novel routes
or exploring unfamiliar environments. In the present study we utilized virtual environments …