Background Prolonged use of anticholinergic and sedative medicines is correlated with
worsening cognition and physical function decline. Deprescribing is a proposed intervention …

Background Mixed findings about deprescribing impact have emerged from varied study
designs, interventions, outcome measures and targeting sub-categories of medications or …

Older people with chronic disease have great potential to benefit from their medications but
are also at high risk of harm from their medications. The use of medications is particularly …

Aims Deprescribing is a suggested intervention to reverse the potential iatrogenic harms of
inappropriate polypharmacy. The review aimed to determine whether or not deprescribing is …

Objectives Deprescribing has been proposed as a way to reduce polypharmacy in frail older
people. We aimed to reduce the number of medicines consumed by people living in …

Background Deprescribing is an intervention to address the high prevalence of
inappropriate polypharmacy in older people living in residential aged care facilities …

Introduction The majority of older people with chronic diseases are prescribed multiple
medicines resulting in polypharmacy. The extrapolation of the 'single disease …

Background Polypharmacy and potentially inappropriate medications (PIMs) are prevalent
in older adults in hospital, and are associated with negative outcomes including adverse …

Objective To evaluate if a pharmacist-led medication review is effective at reducing the
anticholinergic/sedative load, as measured by the Drug Burden Index (DBI). Design …

Polypharmacy is a major challenge in healthcare for older people, and is associated with
increased risks of adverse outcomes, such as delirium, falls, frailty, cognitive impairment and …