Looking back at prospective modeling of outbreak response strategies for managing global type 2 oral poliovirus vaccine (OPV2) cessation

KM Thompson, DA Kalkowska… - Frontiers in Public …, 2023 - frontiersin.org
Introduction Detection of poliovirus transmission and ongoing oral poliovirus vaccine (OPV)
use continue to delay poliomyelitis eradication. In 2016, the Global Polio Eradication …

Coordinated global cessation of oral poliovirus vaccine use: Options and potential consequences

DA Kalkowska, SGF Wassilak, E Wiesen… - Risk …, 2024 - Wiley Online Library
Due to the very low, but nonzero, paralysis risks associated with the use of oral poliovirus
vaccine (OPV), eradicating poliomyelitis requires ending all OPV use globally. The Global …

Updated characterization of outbreak response strategies for 2019–2029: impacts of using a novel type 2 oral poliovirus vaccine strain

DA Kalkowska, MA Pallansch, A Wilkinson… - Risk …, 2021 - Wiley Online Library
Delays in achieving the global eradication of wild poliovirus transmission continue to
postpone subsequent cessation of all oral poliovirus vaccine (OPV) use. Countries must stop …

Expected implications of globally coordinated cessation of serotype 3 oral poliovirus vaccine (OPV) before serotype 1 OPV

DA Kalkowska, KM Thompson - Risk Analysis, 2021 - Wiley Online Library
Globally coordinated cessation of all three serotypes of oral poliovirus vaccine (OPV)
represents a critical part of a successful polio endgame, which the Global Polio Eradication …

[HTML][HTML] Outbreak response strategies with type 2-containing oral poliovirus vaccines

DA Kalkowska, SGF Wassilak, MA Pallansch… - Vaccine, 2023 - Elsevier
Despite exhaustive and fully-financed plans to manage the risks of globally coordinated
cessation of oral poliovirus vaccine (OPV) containing type 2 (OPV2) prior to 2016, as of …

Health and economic consequences of different options for timing the coordinated global cessation of the three oral poliovirus vaccine serotypes

KM Thompson, RJ Duintjer Tebbens - BMC Infectious Diseases, 2015 - Springer
Background World leaders remain committed to globally-coordinated oral poliovirus vaccine
(OPV) cessation following successful eradication of wild polioviruses, but the best timing and …

[HTML][HTML] Serotype 2 oral poliovirus vaccine (OPV2) choices and the consequences of delaying outbreak response

DA Kalkowska, MA Pallansch, SGF Wassilak, SL Cochi… - Vaccine, 2023 - Elsevier
Abstract The Global Polio Eradication Initiative (GPEI) faces substantial challenges with
managing outbreaks of serotype 2 circulating vaccine-derived polioviruses (cVDPV2s) in …

Reflections on modeling poliovirus transmission and the polio eradication endgame

KM Thompson, DA Kalkowska - Risk Analysis, 2021 - Wiley Online Library
Abstract The Global Polio Eradication Initiative (GPEI) partners engaged modelers during
the past nearly 20 years to support strategy and policy discussions and decisions, and to …

[HTML][HTML] Complexity of options related to restarting oral poliovirus vaccine (OPV) in national immunization programs after OPV cessation

DA Kalkowska, SGF Wassilak, E Wiesen… - Gates Open …, 2023 - ncbi.nlm.nih.gov
Background: The polio eradication endgame continues to increase in complexity. With polio
cases caused by wild poliovirus type 1 and circulating vaccine-derived polioviruses of all …

Updated characterization of post‐OPV cessation risks: Lessons from 2019 serotype 2 outbreaks and implications for the probability of OPV restart

DA Kalkowska, MA Pallansch, SL Cochi… - Risk …, 2021 - Wiley Online Library
After the globally coordinated cessation of any serotype of oral poliovirus vaccine (OPV),
some risks remain from undetected, existing homotypic OPV‐related transmission and/or …