Primary pneumonic plague is transmitted easily, progresses rapidly, and causes high
mortality, but the mechanisms by which Yersinia pestis overwhelms the lungs are largely …

A 9.5-kilobase plasmid of Yersinia pestis, the causative agent of plague, is required for high
virulence when mice are inoculated with the bacterium by subcutaneous injection …

Yersinia pestis causes the fatal respiratory disease pneumonic plague. Y. pestis recently
evolved from the gastrointestinal pathogen Y. pseudotuberculosis; however, it is not known …

The plague is caused by the bacterium Yersinia pestis. Plague bacteria are thought to inject
effector Yop proteins into host cells via the type III pathway. The identity of the host cells …

Although pneumonic plague is the deadliest manifestation of disease caused by the
bacterium Yersinia pestis, there is surprisingly little information on the cellular and molecular …

Pneumonic plague is a deadly respiratory disease caused by Yersinia pestis. The bacterial
protease Pla contributes to disease progression and manipulation of host immunity, but the …

Disease progression of primary pneumonic plague is biphasic, consisting of a
preinflammatory and a proinflammatory phase. During the long preinflammatory phase …

A chromosomally encoded protein, which mediates invasion into HeLa cells was recently
identified in Yersinia pseudotuberculosis 1, 2. The role of this protein (invasin) in the …

Yersinia pestis is the aetiological agent of plague, a disease of humans that has potentially
devastating consequences. Evidence indicates that Y. pestis evolved from Yersinia …

Yersinia pestis is transmitted by fleas and causes bubonic plague, characterized by severe
local lymphadenitis that progresses rapidly to systemic infection and life-threatening …