Brain network models of cognitive control are central to advancing our understanding of
psychopathology and cognitive dysfunction in schizophrenia. This review examines the role …

Background Schizophrenia is a highly disabling psychiatric disorder characterized by a
range of positive “psychosis” symptoms. However, the neurobiology of psychosis and …

A large body of neuroimaging literature suggests that distributed regions in the brain form
coordinated largescale networks that show reliable patterns of connectivity when observed …

Background Functional dysconnection in schizophrenia is underwritten by a
pathophysiology of the glutamate neurotransmission that affects the excitation-inhibition …

For effective information processing, two large-scale distributed neural networks appear to
be critical: a multimodal executive system anchored on the dorsolateral prefrontal cortex …

Aberrant salience attribution and cerebral dysconnectivity both have strong evidential
support as core dysfunctions in schizophrenia. Aberrant salience arising from an excess of …

Theories of schizophrenia propose that abnormal functioning of the neural reward system is
linked to negative and psychotic symptoms, by disruption of reward processing and …

Neuroimaging data support the idea that schizophrenia is a brain disorder with altered brain
structure and function. New resting-state functional connectivity techniques allow us to …

Triple network dysfunction theory of schizophrenia postulates that the interaction between
the default-mode and the fronto-parietal executive network is disrupted by aberrant salience …

Effective estimation of the salience of environmental stimuli underlies adaptive behavior,
while related aberrance is believed to undermine rational thought processes in …