Vascular endothelial growth factor (VEGF) is a key regulator of pathological angiogenesis
and vascular permeability and overexpressed by most solid tumors. VEGF receptor-2 …

Background: Blocking vascular endothelial growth factor receptor (VEGFR) is a successful
approach for inhibiting vascular endothelial growth factor (VEGF) signaling. Small molecules …

Vascular endothelial growth factor (VEGF) is a multifunctional angiogenic growth factor that
is a primary stimulant of the development and maintenance of a vascular network in …

Vascular endothelial growth factor (VEGF) plays an important role in both physiological and
pathological angiogenesis. VEGF receptor‑1 (VEGFR‑1) acts as a decoy VEGF receptor that …

Vascular endothelial growth factor A 165 (VEGF-A 165) and VEGF receptor 2 (KDR) are
important mediators of angiogenesis. We aimed to express the soluble KDR ligand-binding …

Biological evidence suggests that interference with the function of the angiogenic growth
factor receptor VEGFR2 (flk1/KDR) is a particularly promising strategy to inhibit tumor …

Angiogenesis is a process of development and of growth of new capillary blood vessels from
pre-existing vessels. When pathological, it contributes to the development of numerous …

Vascular endothelial growth factor (VEGF), one of the most important angiogenic factors,
plays an essential role in both physiological and pathological angiogenesis. The VEGF …

The interaction of vessel endothelial cell growth factor (VEGF) and its receptors (flt-1, FLK-
1/KDR) regulates tumor angiogenesis. Therefore, blocking the binding of VEGF and the …

Vascular endothelial growth factor (VEGF) plays a pivotal role in the processes of
angiogenesis, which is essential for the growth of solid tumors and their metastasis …