Recent progress and trends in X-ray-induced photodynamic therapy with low radiation doses

L He, X Yu, W Li - ACS nano, 2022 - ACS Publications
The prominence of photodynamic therapy (PDT) in treating superficial skin cancer inspires
innovative solutions for its congenitally deficient shadow penetration of the visible-light …

[HTML][HTML] Nanoscintillator-mediated X-ray induced photodynamic therapy for deep-seated tumors: from concept to biomedical applications

W Sun, Z Zhou, G Pratx, X Chen, H Chen - Theranostics, 2020 - ncbi.nlm.nih.gov
Photodynamic therapy (PDT) has shown great effectiveness in oncotherapy but has not
been implemented in broad clinical applications because the limited penetration depth of …

Progress in the development of nanosensitizers for X-ray-induced photodynamic therapy

XD Ren, XY Hao, HC Li, MR Ke, BY Zheng… - Drug Discovery …, 2018 - Elsevier
Highlights•X-ray-induced photodynamic (X-PDT) is a new approach to tackle deep tumors.•X-
ray-induced sensitizers (XSs) are the key to X-PDT.•The development of XSs is discussed in …

[HTML][HTML] X-ray induced photodynamic therapy: A combination of radiotherapy and photodynamic therapy

GD Wang, HT Nguyen, H Chen, PB Cox, L Wang… - Theranostics, 2016 - ncbi.nlm.nih.gov
Conventional photodynamic therapy (PDT)'s clinical application is limited by depth of
penetration by light. To address the issue, we have recently developed X-ray induced …

Nanoscintillator-mediated X-ray inducible photodynamic therapy for in vivo cancer treatment

H Chen, GD Wang, YJ Chuang, Z Zhen, X Chen… - Nano …, 2015 - ACS Publications
Photodynamic therapy is a promising treatment method, but its applications are limited by
the shallow penetration of visible light. Here, we report a novel X-ray inducible …

Nanoparticles to mediate X‐ray‐induced photodynamic therapy and Cherenkov radiation photodynamic therapy

B Cline, I Delahunty, J Xie - Wiley Interdisciplinary Reviews …, 2019 - Wiley Online Library
Photodynamic therapy (PDT) has emerged as an attractive option for cancer treatment.
However, conventional PDT is activated by light that has poor tissue penetration depths …

Using X-rays in photodynamic therapy: an overview

L Larue, AB Mihoub, Z Youssef, L Colombeau… - Photochemical & …, 2018 - pubs.rsc.org
Photodynamic therapy is a therapeutic option to treat cancer and other diseases. PDT is
used every day in dermatology, and recent developments in the treatment of glioblastoma …

Advanced techniques for performing photodynamic therapy in deep-seated tissues

B Sun, JNB Rahmat, Y Zhang - Biomaterials, 2022 - Elsevier
Photodynamic therapy (PDT) is a promising localized cancer treatment modality. It has been
used successfully to treat a range of dermatological conditions with comparable efficacy to …

Evolution of nanoparticle-mediated photodynamic therapy: from superficial to deep-seated cancers

M Sivasubramanian, YC Chuang, LW Lo - Molecules, 2019 - mdpi.com
Enthusiasm for photodynamic therapy (PDT) as a potential therapeutic intervention for
cancer has increased exponentially in recent decades. Photodynamic therapy constitutes a …

The use of nanomaterials in advancing photodynamic therapy (PDT) for deep-seated tumors and synergy with radiotherapy

D Dinakaran, BC Wilson - Frontiers in Bioengineering and …, 2023 - frontiersin.org
Photodynamic therapy (PDT) has been under development for at least 40 years. Multiple
studies have demonstrated significant anti-tumor efficacy with limited toxicity concerns. PDT …