Living Bacteria‐Based Immuno‐Photodynamic Therapy: Metabolic Labeling of Clostridium butyricum for Eradicating Malignant Melanoma
Due to the complexity, aggressiveness, and heterogeneity of malignant melanoma, it is
difficult to eradicate the whole tumor through conventional treatment. Herein, a strategy of …
difficult to eradicate the whole tumor through conventional treatment. Herein, a strategy of …
Photodynamic treatment of tumor with bacteria expressing killerred
L Yan, M Kanada, J Zhang, S Okazaki, S Terakawa - PloS one, 2015 - journals.plos.org
Photodynamic therapy (PDT) is a cancer treatment modality in which a photosensitizing dye
is administered and exposed to light to kill tumor cells via the production of reactive oxygen …
is administered and exposed to light to kill tumor cells via the production of reactive oxygen …
Engineering bioluminescent bacteria to boost photodynamic therapy and systemic anti-tumor immunity for synergistic cancer treatment
The limited penetration depth of external excitation light would remarkably impair the
therapeutic efficacy of photodynamic therapy (PDT) and its clinical utilization. Herein, we …
therapeutic efficacy of photodynamic therapy (PDT) and its clinical utilization. Herein, we …
Photosensitizer-bacteria biohybrids promote photodynamic cancer cell ablation and intracellular protein delivery
Live bacteria have drawn widespread interest as carriers to deliver genes and proteins into
eukaryotic cells for the treatment of various cancer types owing to their good biocompatibility …
eukaryotic cells for the treatment of various cancer types owing to their good biocompatibility …
Photothermal Lysis of Engineered Bacteria to Modulate Amino Acid Metabolism against Tumors
M Sun, M Yang, S Li, C Wang, F Zhang… - Advanced Functional …, 2023 - Wiley Online Library
Bacterial‐mediated synergistic cancer therapy (BMSCT) is used as a promising tumor
therapy approach. However, there are some disadvantages of bacterial therapy alone to be …
therapy approach. However, there are some disadvantages of bacterial therapy alone to be …
Engineered NIR light-responsive bacteria as anti-tumor agent for targeted and precise cancer therapy
H Pan, L Li, G Pang, C Han, B Liu, Y Zhang… - Chemical Engineering …, 2021 - Elsevier
Engineered anaerobic bacteria known as live biotherapeutic products (LBPs) have shown
great advances in cancer therapy. One advantage of anaerobic bacteria as drug carrier is …
great advances in cancer therapy. One advantage of anaerobic bacteria as drug carrier is …
Bacterial targeted AIE photosensitizers synergistically promote chemotherapy for the treatment of inflammatory cancer
Tumor-associated components, especially extratumoral bacteria (EB) in the form of biofilms,
could exacerbate cancer progression and hinder the effectiveness of antitumor drugs by …
could exacerbate cancer progression and hinder the effectiveness of antitumor drugs by …
Metabolically engineered bacteria as light-controlled living therapeutics for anti-angiogenesis tumor therapy
A living therapeutic system based on attenuated Salmonella was developed via metabolic
engineering using an aggregation-induced emission (AIE) photosensitizer MA. The …
engineering using an aggregation-induced emission (AIE) photosensitizer MA. The …
Surface programmed bacteria as photo-controlled NO generator for tumor immunological and gas therapy
B Chen, X Zhang, L Cheng, X Chen, J Tang… - Journal of Controlled …, 2023 - Elsevier
The use of bacteria as living vehicles has attracted increasing attentions in tumor therapy
field. The combination of functional materials with bacteria dramatically facilitates the …
field. The combination of functional materials with bacteria dramatically facilitates the …
Optically activatable photosynthetic bacteria-based highly tumor specific immunotheranostics
Despite the growing promise of bacterial therapy, due to the tumor targeting effect, in solid
tumor treatment, most conventional therapeutic bacteria exhibit pathogenicity and …
tumor treatment, most conventional therapeutic bacteria exhibit pathogenicity and …
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