Synthesis, characterization, DFT studies and evaluation of the potential anti-tumour activity of nicotinic hydrazide based Schiff base using in vitro and molecular …
V Preethi, VG Vijukumar, S AnilaRaj, VG Vidya - Heliyon, 2024 - cell.com
Breast cancer, one of the most serious issues worldwide, has been raising day by day. It has
now become a necessary to develop a suitable drug to combat this terrible illness. Schiff …
now become a necessary to develop a suitable drug to combat this terrible illness. Schiff …
Experimental, spectroscopic, and theoretical investigation on structural and anticancer activities of Schiff bases derived from isonicotinohydrazide
Isoniazid hydrazones are promising possibilities as medicines since they have preserved
efficacy and are less toxic and resistant to resistance than parent Isoniazid (INH). Here, we …
efficacy and are less toxic and resistant to resistance than parent Isoniazid (INH). Here, we …
In-silico molecular docking, ADMET and DFT evaluation of piperidin-4-one furoic hydrazone derivatives as antimicrobial, antioxidant and anticancer agents
M Sivanandhan, U Seeman, A Parasuraman - Journal of the Iranian …, 2024 - Springer
Abstract A series of N'-(2, 6-diarylpiperidin-4-ylidene) furan-2-carbohydrazide were
synthesized by incorporating hydrazide group in piperidine moiety and characterized by IR …
synthesized by incorporating hydrazide group in piperidine moiety and characterized by IR …
Quantum computational, spectroscopic investigation, molecular docking, and in vitro pharmacological studies of sulfonamide Schiff base
A new Schiff base,(E)-4-((3, 5-dibromo-2-hydroxybenzylidene) amino)-N-(5-methylisoxazol-
3-yl) benzenesulfonamide was synthesized and characterized by various physico-chemical …
3-yl) benzenesulfonamide was synthesized and characterized by various physico-chemical …
A New Schiff Base Molecule Prepared from Pyrimidine-2-thione: Synthesis, Spectral Characterization, Cytotoxic Activity, DFT, and Molecular Docking Studies
Z KÖKBUDAK, B TÜRKMENOĞLU… - … University Journal of …, 2022 - dergipark.org.tr
Schiff base derivatives are some of the most widely used organic compounds for industrial
purposes and they exhibit a broad range of biological activities. In this paper, a new Schiff …
purposes and they exhibit a broad range of biological activities. In this paper, a new Schiff …
Synthesis, characterization, anti-proliferative activity and chemistry computation of DFT theoretical methods of hydrazine-based Schiff bases derived from methyl …
S Parvarinezhad, M Salehi - Journal of Molecular Structure, 2021 - Elsevier
In this study, the synthesized hydrazine Schiff bases belonging to methyl acetoacetate (1)
and α-hydroxyacetophenone (2) were prepared by simple methods. In addition, FT-IR, UV …
and α-hydroxyacetophenone (2) were prepared by simple methods. In addition, FT-IR, UV …
Synthesis, characterization, and biological properties of novel Schiff bases containing pentafluorophenyl hydrazine
F Hamurcu - Journal of Biochemical and Molecular Toxicology, 2023 - Wiley Online Library
In the present study, new Schiff bases derived from pentafluorophenyl‐hydrazine (L1, L2,
L3, L4) were synthesized and their structures were characterized by 1H nuclear magnetic …
L3, L4) were synthesized and their structures were characterized by 1H nuclear magnetic …
Design, synthesis, anti-proliferative, anti-microbial, anti-angiogenic activity and in silico analysis of novel hydrazone derivatives
Background: Cancer is the second leading cause of death globally. Hydrazone and
hydrazone derivatives have high activity, and for this reason, these compound are greatly …
hydrazone derivatives have high activity, and for this reason, these compound are greatly …
Synthesis, structure–activity relationship studies using density functional theory and in silico molecular docking on substituted benzohydrazide derivatives
The present study demonstrates the utility of benzohydrazide derivatives based on an
approach to identify potential targets for a series of synthesized compounds that show potent …
approach to identify potential targets for a series of synthesized compounds that show potent …
Schiff base (Z)-4-((furan-2-ylmethylene) amino) benzenesulfonamide: synthesis, solvent interactions through hydrogen bond, structural and spectral properties …
S Manivel, BS Gangadharappa, N Elangovan… - Journal of Molecular …, 2022 - Elsevier
A new Schiff base (Z)-4-((furan-2-ylmethylene) amino) benzenesulfonamide (FURNI) was
synthesized by the reaction reaction between furfural and sulfanilamide followed by …
synthesized by the reaction reaction between furfural and sulfanilamide followed by …