Mixture design applied in compatibility studies of catechin and lipid compounds

R Ferreira-Nunes, T Gratieri, GM Gelfuso… - … of pharmaceutical and …, 2018 - Elsevier
The aim of this work was to evaluate the compatibility of (+)-catechin (CA) and excipients
commonly used to prepare micro and nanoemulsions using thermal analysis along with …

Compatibility study between lipoic acid with polymers used in controlled drug release systems

PCD Silva, AS Portela, RSC Lima, CP Santana… - Journal of Thermal …, 2016 - Springer
Lipoic acid is derived from octanoic acid and is considered a universal antioxidant for
combating free radicals and regeneration of endogenous antioxidant, as well as acting like …

Guest–host interactions and complex formation for artemisinin with cyclodextrins: instrumental analysis and evaluation of biological activity

D Circioban, A Ledeti, G Vlase, D Coricovac… - Journal of Thermal …, 2018 - Springer
Artemisinin is one of the most important naturally occurring compound found in Artemisia
annua, being highly active against Plasmodium falciparum, the malaria causing parasite …

Use of mixture design in drug-excipient compatibility determinations: Thymol nanoparticles case study

FQ Pires, T Angelo, JKR Silva, LCL Sá-Barreto… - … of pharmaceutical and …, 2017 - Elsevier
The objective of this work was to access thymol-excipient compatibility using an alternative
protocol of mixture design subsidizing the development of nanostructures lipid carriers …

Evaluation of carvedilol compatibility with lipid excipients for the development of lipid-based drug delivery systems

LAD Silva, FV Teixeira, RC Serpa, NL Esteves… - Journal of thermal …, 2016 - Springer
Carvedilol (CARV) is a widely used non-selective β-blocker, which has shown low
bioavailability after oral administration (20%) due to its low water solubility and intense first …

Further characterization of theobroma oil–beeswax admixtures as lipid matrices for improved drug delivery systems

AA Attama, BC Schicke, CC Müller-Goymann - European Journal of …, 2006 - Elsevier
There is an increasing interest in lipid based drug delivery systems due to factors such as
better characterization of lipidic excipients and formulation versatility and the choice of …

Influence of surfactant on the thermal behavior of marigold oil emulsions with liquid crystal phases

ODH dos Santos, PA da Rocha-Filho - Drug Development and …, 2007 - Taylor & Francis
Vegetable oils have been largely consumed owing to the interest of pharmaceutical and
cosmetic industries in using natural raw materials. The production of stable emulsions with …

A way for improving the stability of the essential oils in an environmental friendly formulation

M Răileanu, L Todan, M Voicescu, C Ciuculescu… - Materials Science and …, 2013 - Elsevier
The essential oils (EOs) possess amazing properties explaining the interest for their
applications in many essential domains. They also present the disadvantage of their …

DSC supported by factor analysis as a reliable tool for compatibility study in pharmaceutical mixtures

B Rojek, M Wesolowski - Journal of Thermal Analysis and Calorimetry, 2019 - Springer
A chemometrically optimized DSC interpretation was developed for the identification of
compatibility/incompatibility between active pharmaceutical ingredients (APIs) and …

Mediterranean essential oils as precious matrix components and active ingredients of lipid nanoparticles

C Carbone, C Martins-Gomes, C Caddeo… - International Journal of …, 2018 - Elsevier
Essential oils are recognized as valuable active pharmaceutical ingredients attributed to a
set of biological properties, which include antibacterial, antifungal, antiviral, antioxidant …