Diagnostic histone modification analysis of individual preimplantation embryos
Y Zeng, Y Hoshino, K Susami, S Honda, N Minami… - bioRxiv, 2023 - biorxiv.org
Background: We previously reported a modification of the CUT&Tag method (NTU-CAT) that
allows genome-wide histone modification analysis in individual preimplantation embryos. In …
allows genome-wide histone modification analysis in individual preimplantation embryos. In …
Evaluating histone modification analysis of individual preimplantation embryos
Y Zeng, Y Hoshino, K Susami, S Honda, N Minami… - BMC genomics, 2024 - Springer
Background We previously reported a modification of the CUT&Tag method (NTU-CAT) that
allows genome-wide histone modification analysis in individual preimplantation embryos. In …
allows genome-wide histone modification analysis in individual preimplantation embryos. In …
Genome-wide profiling of histone H3K4me3 and H3K27me3 modifications in individual blastocysts by CUT&Tag without a solid support (NON-TiE-UP CUT&Tag)
K Susami, S Ikeda, Y Hoshino, S Honda, N Minami - Scientific Reports, 2022 - nature.com
Individual analysis of the epigenome of preimplantation embryos is useful for characterizing
each embryo and for investigating the effects of environmental factors on their epigenome …
each embryo and for investigating the effects of environmental factors on their epigenome …
Tn5 transposase-based epigenomic profiling methods are prone to open chromatin bias
Epigenetic studies of rare biological samples like mammalian oocytes and preimplantation
embryos require low input or even single cell epigenomic profiling methods. To reduce …
embryos require low input or even single cell epigenomic profiling methods. To reduce …
Current status of genome‐wide epigenetic profiling of mammalian preimplantation embryos
S Ikeda - Reproductive Medicine and Biology, 2023 - Wiley Online Library
Background Genome‐wide information on epigenetic modifications in mammalian
preimplantation embryos was an unexplored sanctuary of valuable research insights …
preimplantation embryos was an unexplored sanctuary of valuable research insights …
BEYOND CHROMOSOMAL ABERRATIONS–TRANSCRIPTOMIC PROFILES OF ANEUPLOID, MOSAIC, AND EUPLOID EMBRYOS FROM TROPHECTODERM …
S Madjunkova, B Wyse, NF Weizman, R Kharonsky… - Fertility and …, 2022 - fertstert.org
Objective The effects of aberrant chromosome dosage on gene expression and the
mechanisms that regulate the transcriptional processes in preimplantation embryos are …
mechanisms that regulate the transcriptional processes in preimplantation embryos are …
Genome-wide histone modification profiling of inner cell mass and trophectoderm of bovine blastocysts by RAT-ChIP
T Org, K Hensen, R Kreevan, E Mark, O Sarv… - PLoS …, 2019 - journals.plos.org
Chromatin immunoprecipitation coupled with next-generation sequencing (ChIP-seq) has
revolutionized our understanding of chromatin-related biological processes. The method …
revolutionized our understanding of chromatin-related biological processes. The method …
Analytical validation of a novel next-generation sequencing based preimplantation genetic screening technology
J Gole, T Mullen, G Celia, C Wagner, B Kaplan… - Fertility and …, 2016 - fertstert.org
Background Current data indicate that preimplantation genetic screening (PGS) increases
live birth and decreases miscarriage rates. However, high cost has limited its adoption. This …
live birth and decreases miscarriage rates. However, high cost has limited its adoption. This …
Histone remodeling reflects conserved mechanisms of bovine and human preimplantation development
C Zhou, MM Halstead, A Bonnet‐Garnier… - EMBO …, 2023 - embopress.org
How histone modifications regulate changes in gene expression during preimplantation
development in any species remains poorly understood. Using CUT&Tag to overcome …
development in any species remains poorly understood. Using CUT&Tag to overcome …
Analysis of accessible chromatin landscape in the inner cell mass and trophectoderm of human blastocysts
M Yang, X Tao, S Titus, T Zhao… - Molecular Human …, 2020 - academic.oup.com
Early embryonic development is characterized by drastic changes in chromatin structure that
affects the accessibility of the chromatin. In human, the chromosome reorganization and its …
affects the accessibility of the chromatin. In human, the chromosome reorganization and its …