Maternal obesity increases the risk of childhood obesity and programs the offspring to
develop metabolic syndrome later in their life. Palmitate is the predominant saturated free …

Pre-pregnancy body mass index determines pregnancy outcome (Nelson et al. 2010, Flegal
et al. 2012), and more than half of pregnant women in the United States are overweight or …

Introduction Obesity during pregnancy increases the risk for maternal complications like
gestational diabetes, preeclampsia, and maternal inflammation. Maternal obesity also …

During gestation, excess palmitate (PA) is enriched in decidua. Both excess PA and
decidual dysfunctions are associated with numerous adverse pregnancy outcomes such as …

Introduction There is an increasing prevalence of non-communicable diseases worldwide.
Metabolic diseases such as obesity and gestational diabetes mellitus (GDM) increasingly …

Obesity is associated with low-grade chronic inflammation, which contributes to cellular
dysfunction promoting metabolic disease. Obesity during pregnancy leads to a …

High levels of proinflammatory cytokines have been observed in obese pregnancies.
Obesity during pregnancy may increase the risk of various pregnancyrelated complications …

A critical component of early human placental development includes migration of
extravillous trophoblasts (EVTs) into the decidua. EVTs migrate toward and displace …

Background Palmitic acid (PA), the main component of dietary saturated fat, causes
apoptosis in many cell types, including mouse granulosa cell. Melatonin, an important …

Free fatty acids (FFAs) are energy substrates for many cell types, but in excess, some FFAs
can accumulate in nonadipose cells, inducing apoptosis. Also known as lipotoxicity, this …