Current evidences suggest that hyperuricemia is closely related to the overproduction or
underexcretion of uric acid (UA). Curcumin (CUR), a natural polyphenol component …

Nuciferine, a major aporphine alkaloid of the leaves of Nelumbo nucifera, was found to
decrease serum urate levels and improved kidney function, as well as inhibited system and …

Background Hyperuricemia (HUA) is an important risk factor for renal diseases and
contributes to renal fibrosis. It has been proved that phloretin has antioxidant and anti …

Abstract Ethnopharmacological relevance Wuling San, a famous prescription in Chinese
medicine, is composed of Polyporus, Poria, Alismatis rhizoma, Cinnamomi cortex and …

Inflammation plays a pivotal role in the pathogenesis of diabetic nephropathy (DN).
Overexpression of inflammatory chemokine and cytokines is involved in the development of …

It is well known that the progression of hyperuricemia disease often contributes to renal
dysfunction. However, there have been few studies on uric acid nephropathy (UAN) …

Purpose Gouty arthritis is generally induced by the accumulation of monosodium urate
(MSU) crystals in the joints due to elevated serum uric acid levels, potentially leading to …

Background Monosodium urate (MSU) crystals‐induced inflammation is a key initiator in
gouty arthritis. Curcumin is an active ingredient possessing anti‐inflammatory efficacy. But …

Hyperuricemia is the main cause of gout and involved in the occurrence of many other
diseases such as hyperlipidemia and hypertension correlated with metabolic disorders …

This study investigated if the nephroprotective effect of Curcumin in streptozotocin-induced
type 1 diabetes mellitus (DM) in rats involves downregulation/inhibition of p 66 Shc and …