Clinical and metabolic response to probiotic administration in people with Parkinson's disease: a randomized, double-blind, placebo-controlled trial

OR Tamtaji, M Taghizadeh, RD Kakhaki, E Kouchaki… - Clinical Nutrition, 2019 - Elsevier
Background & aims The investigation was done to assess the impacts of probiotic
supplementation on movement and metabolic parameters in individuals with Parkinson's …

Probiotics synergized with conventional regimen in managing Parkinson's disease

H Sun, F Zhao, Y Liu, T Ma, H Jin, K Quan… - npj Parkinson's …, 2022 - nature.com
Parkinson's disease (PD) is mainly managed by pharmacological therapy (eg, Benserazide
and dopamine agonists). However, prolonged use of these drugs would gradually diminish …

Probiotics for Parkinson's disease: Current evidence and future directions

AH Tan, JW Hor, CW Chong, SY Lim - JGH Open, 2021 - Wiley Online Library
The gut–brain axis is a hot topic in Parkinson's disease (PD). It has been postulated that gut
pathogens and dysbiosis can contribute to peripheral inflammatory states or trigger …

Neurogenic and anti-inflammatory effects of probiotics in Parkinson's disease: A systematic review of preclinical and clinical evidence

V Leta, KR Chaudhuri, O Milner, G Chung-Faye… - Brain, Behavior, and …, 2021 - Elsevier
There is increasing evidence highlighting the potential role of the gut-brain axis in the
pathogenesis of Parkinson's disease (PD) and on the use of probiotics as a therapeutic …

Role of the gut–brain axis, gut microbial composition, diet, and probiotic intervention in Parkinson's disease

S Thangaleela, BS Sivamaruthi, P Kesika, M Bharathi… - Microorganisms, 2022 - mdpi.com
Parkinson's disease (PD) is the second-most prevalent neurodegenerative or
neuropsychiatric disease, affecting 1% of seniors worldwide. The gut microbiota (GM) is one …

An open label, non-randomized study assessing a prebiotic fiber intervention in a small cohort of Parkinson's disease participants

DA Hall, RM Voigt, TM Cantu-Jungles… - Nature …, 2023 - nature.com
A pro-inflammatory intestinal microbiome is characteristic of Parkinson's disease (PD).
Prebiotic fibers change the microbiome and this study sought to understand the utility of …

[PDF][PDF] The effects of probiotic supplementation on gene expression related to inflammation, insulin and lipid in patients with Parkinson's disease: a randomized …

S Borzabadi, S Oryan, A Eidi, Z Asemi - Archives of Iranian medicine, 2018 - journalaim.com
Background: This study was conducted to evaluate the effects of probiotic supplementation
on gene expression related to inflammation, insulin and lipid in patients with Parkinson's …

A nutritional approach to microbiota in Parkinson's disease

GÖ Uyar, H Yildiran - Bioscience of Microbiota, Food and Health, 2019 - jstage.jst.go.jp
Parkinson's disease (PD) is a neurodegenerative disease characterized by motor
impairment and the accumulation of alpha-synucleinopathy (α-syn), which can affect …

Probiotics May Have Beneficial Effects in Parkinson's Disease: In vitro Evidence

L Magistrelli, A Amoruso, L Mogna, T Graziano… - Frontiers in …, 2019 - frontiersin.org
Background: Parkinson's disease (PD) is characterized by loss of dopaminergic neurons
and intraneuronal accumulation of alpha-synuclein, both in the basal ganglia and in …

Probiotics for Parkinson's disease

P Gazerani - International journal of molecular sciences, 2019 - mdpi.com
Parkinson's disease (PD) is a complex neurological disorder classically characterized by
impairments in motor system function associated with loss of dopaminergic neurons in the …