Chlamydia trachomatis Polymorphic Membrane Proteins (Pmps) Form Functional Homomeric and Heteromeric Oligomers

A Favaroni, JH Hegemann - Frontiers in Microbiology, 2021 - frontiersin.org
Chlamydiae are Gram-negative, obligate intracellular bacteria, which infect animals and
humans. Adhesion to host cells, the first step in the infection process, is mediated by …

A structural foundation for studying chlamydial polymorphic membrane proteins

AM Debrine, PA Karplus, DD Rockey - Microbiology Spectrum, 2023 - Am Soc Microbiol
Polymorphic membrane proteins (Pmps) are chlamydial cell surface proteins with signature
repeating FxxN and GGA (I, V, L) tetrapeptide motifs. These autotransporter proteins are key …

All subtypes of the Pmp adhesin family are implicated in chlamydial virulence and show species‐specific function

E Becker, JH Hegemann - Microbiologyopen, 2014 - Wiley Online Library
The bacterial pathogens Chlamydia trachomatis and C. pneumoniae are obligate
intracellular parasites, cause a number of serious diseases, and can infect various cell types …

Chlamydial polymorphic membrane proteins: regulation, function and potential vaccine candidates

S Vasilevsky, M Stojanov, G Greub, D Baud - Virulence, 2016 - Taylor & Francis
Pmps (Polymorphic Membrane Proteins) are a group of membrane bound surface exposed
chlamydial proteins that have been characterized as autotransporter adhesins and are …

Processing of Chlamydia abortus Polymorphic Membrane Protein 18D during the Chlamydial Developmental Cycle

NM Wheelhouse, M Sait, K Aitchison, M Livingstone… - PloS one, 2012 - journals.plos.org
Background Chlamydia possess a unique family of autotransporter proteins known as the
Polymorphic membrane proteins (Pmps). While the total number of pmp genes varies …

Sequence, structure prediction, and epitope analysis of the polymorphic membrane protein family in Chlamydia trachomatis

PW Cervantes, BW Segelke, EY Lau, BV Robinson… - Plos one, 2024 - journals.plos.org
The polymorphic membrane proteins (Pmps) are a family of autotransporters that play an
important role in infection, adhesion and immunity in Chlamydia trachomatis. Here we show …

Variable expression of surface‐exposed polymorphic membrane proteins in in vitro‐grown Chlamydia trachomatis

C Tan, R Hsia, H Shou, JA Carrasco… - Cellular …, 2010 - Wiley Online Library
The hypothesized variable expression of polymorphic membrane proteins (PmpA–PmpI) in
Chlamydia trachomatis‐infected patients was tested by examination of the expression of …

Expression, Processing, and Localization of PmpD of Chlamydia trachomatis Serovar L2 during the Chlamydial Developmental Cycle

AO Kiselev, WE Stamm, JR Yates, MF Lampe - PLoS One, 2007 - journals.plos.org
Background While families of polymorphic membrane protein (pmp) genes have been
identified in several Chlamydia species, their function remains mostly unknown. These …

Analysis of pmpD Expression and PmpD Post-Translational Processing during the Life Cycle of Chlamydia trachomatis Serovars A, D, and L2

AO Kiselev, MC Skinner, MF Lampe - PLoS One, 2009 - journals.plos.org
Background The polymorphic membrane protein D (PmpD) in Chlamydia is structurally
similar to autotransporter proteins described in other bacteria and may be involved in …

Members of the Pmp protein family of Chlamydia pneumoniae mediate adhesion to human cells via short repetitive peptide motifs

K Mölleken, E Schmidt… - Molecular microbiology, 2010 - Wiley Online Library
Chlamydiae sp. are obligate intracellular pathogens that cause a variety of diseases in
humans. Adhesion of the infectious elementary body to the eukaryotic host cell is a pivotal …