Competing endogenous RNA networks as biomarkers in neurodegenerative diseases
L Moreno-García, T López-Royo, AC Calvo… - International journal of …, 2020 - mdpi.com
Protein aggregation is classically considered the main cause of neuronal death in
neurodegenerative diseases (NDDs). However, increasing evidence suggests that alteration …
neurodegenerative diseases (NDDs). However, increasing evidence suggests that alteration …
Noncoding RNA crosstalk in brain health and diseases
The mammalian brain expresses several classes of noncoding RNAs (ncRNAs), including
long ncRNAs (lncRNAs), circular RNAs (circRNAs), and microRNAs (miRNAs). These …
long ncRNAs (lncRNAs), circular RNAs (circRNAs), and microRNAs (miRNAs). These …
Long non-coding RNAs and circular RNAs: insights into microglia and astrocyte mediated neurological diseases
M Chen, X Lai, X Wang, J Ying, L Zhang… - Frontiers in Molecular …, 2021 - frontiersin.org
Microglia and astrocytes maintain tissue homeostasis in the nervous system. Both microglia
and astrocytes have pro-inflammatory phenotype and anti-inflammatory phenotype …
and astrocytes have pro-inflammatory phenotype and anti-inflammatory phenotype …
Functional roles and networks of non-coding RNAs in the pathogenesis of neurodegenerative diseases
YY Wu, HC Kuo - Journal of Biomedical Science, 2020 - Springer
Recent transcriptome analyses have revealed that noncoding RNAs (ncRNAs) are broadly
expressed in mammalian cells and abundant in the CNS, with tissue and cell type-specific …
expressed in mammalian cells and abundant in the CNS, with tissue and cell type-specific …
Non-coding RNAs in nervous system development and disease
B Salvatori, S Biscarini, M Morlando - Frontiers in cell and …, 2020 - frontiersin.org
The rapid advance of RNA sequencing technologies contributed to a deep understanding of
transcriptome composition and has allowed the discovery of a large number of non-coding …
transcriptome composition and has allowed the discovery of a large number of non-coding …
Neurodegeneration as an RNA disorder
Neurodegenerative diseases constitute one of the single most important public health
challenges of the coming decades, and yet we presently have only a limited understanding …
challenges of the coming decades, and yet we presently have only a limited understanding …
Long-noncoding RNAs as epigenetic regulators in neurodegenerative diseases
P Ruffo, F De Amicis, E Giardina… - Neural regeneration …, 2023 - journals.lww.com
The growing and rapid development of high-throughput sequencing technologies have
allowed a greater understanding of the mechanisms underlying gene expression regulation …
allowed a greater understanding of the mechanisms underlying gene expression regulation …
Roles of non-coding RNA in alzheimer's disease pathophysiology
EO Olufunmilayo, RMD Holsinger - International journal of molecular …, 2023 - mdpi.com
Alzheimer's disease (AD) is a chronic neurodegenerative disorder that is accompanied by
deficits in memory and cognitive functions. The disease is pathologically characterised by …
deficits in memory and cognitive functions. The disease is pathologically characterised by …
Competing endogenous RNA regulations in neurodegenerative disorders: current challenges and emerging insights
Y Cai, J Wan - Frontiers in molecular neuroscience, 2018 - frontiersin.org
The past decade has witnessed exciting breakthroughs that have contributed to the richness
and complexity of a burgeoning modern RNA world, and one particular breakthrough—the …
and complexity of a burgeoning modern RNA world, and one particular breakthrough—the …
Noncoding RNAs in neurodegeneration
E Salta, B De Strooper - Nature Reviews Neuroscience, 2017 - nature.com
The emerging complexity of the transcriptional landscape poses great challenges to our
conventional preconceptions of how the genome regulates brain function and dysfunction …
conventional preconceptions of how the genome regulates brain function and dysfunction …